Connell PP - Search Results

1

Optimization of Drug Candidates That Inhibit the D-Loop Activity of RAD51.

Budke B, Tueckmantel W, Miles K, Kozikowski AP, Connell PP. Budke B, et al. Among authors: connell pp. ChemMedChem. 2019 May 17;14(10):1031-1040. doi: 10.1002/cmdc.201900075. Epub 2019 Apr 17. ChemMedChem. 2019. PMID: 30957434 Free PMC article.

2

Pilot study examining tumor expression of RAD51 and clinical outcomes in human head cancers.

Connell PP, Jayathilaka K, Haraf DJ, Weichselbaum RR, Vokes EE, Lingen MW. Connell PP, et al. Int J Oncol. 2006 May;28(5):1113-9. Int J Oncol. 2006. PMID: 16596227

3

A chemical compound that stimulates the human homologous recombination protein RAD51.

Jayathilaka K, Sheridan SD, Bold TD, Bochenska K, Logan HL, Weichselbaum RR, Bishop DK, Connell PP. Jayathilaka K, et al. Among authors: connell pp. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15848-53. doi: 10.1073/pnas.0808046105. Epub 2008 Oct 7. Proc Natl Acad Sci U S A. 2008. PMID: 18840682 Free PMC article.

4

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells.

Budke B, Logan HL, Kalin JH, Zelivianskaia AS, Cameron McGuire W, Miller LL, Stark JM, Kozikowski AP, Bishop DK, Connell PP. Budke B, et al. Among authors: connell pp. Nucleic Acids Res. 2012 Aug;40(15):7347-57. doi: 10.1093/nar/gks353. Epub 2012 May 9. Nucleic Acids Res. 2012. PMID: 22573178 Free PMC article.

5

An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.

Budke B, Kalin JH, Pawlowski M, Zelivianskaia AS, Wu M, Kozikowski AP, Connell PP. Budke B, et al. Among authors: connell pp. J Med Chem. 2013 Jan 10;56(1):254-63. doi: 10.1021/jm301565b. Epub 2012 Dec 26. J Med Chem. 2013. PMID: 23231413 Free PMC article.

6

Real-time solution measurement of RAD51- and RecA-mediated strand assimilation without background annealing.

Budke B, Chan YL, Bishop DK, Connell PP. Budke B, et al. Among authors: connell pp. Nucleic Acids Res. 2013 Jul;41(13):e130. doi: 10.1093/nar/gkt362. Epub 2013 May 10. Nucleic Acids Res. 2013. PMID: 23666628 Free PMC article.

7

DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.

Pitroda SP, Pashtan IM, Logan HL, Budke B, Darga TE, Weichselbaum RR, Connell PP. Pitroda SP, et al. Among authors: connell pp. Sci Transl Med. 2014 Mar 26;6(229):229ra42. doi: 10.1126/scitranslmed.3008291. Sci Transl Med. 2014. PMID: 24670686 Free PMC article.

8

The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.

Mason JM, Logan HL, Budke B, Wu M, Pawlowski M, Weichselbaum RR, Kozikowski AP, Bishop DK, Connell PP. Mason JM, et al. Among authors: connell pp. Cancer Res. 2014 Jul 1;74(13):3546-55. doi: 10.1158/0008-5472.CAN-13-3220. Epub 2014 Apr 21. Cancer Res. 2014. PMID: 24753542 Free PMC article.

9

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.

Mason JM, Dusad K, Wright WD, Grubb J, Budke B, Heyer WD, Connell PP, Weichselbaum RR, Bishop DK. Mason JM, et al. Among authors: connell pp. Nucleic Acids Res. 2015 Mar 31;43(6):3180-96. doi: 10.1093/nar/gkv175. Epub 2015 Mar 12. Nucleic Acids Res. 2015. PMID: 25765654 Free PMC article.

10

Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration.

Thierry S, Benleulmi MS, Sinzelle L, Thierry E, Calmels C, Chaignepain S, Waffo-Teguo P, Merillon JM, Budke B, Pasquet JM, Litvak S, Ciuffi A, Sung P, Connell P, Hauber I, Hauber J, Andreola ML, Delelis O, Parissi V. Thierry S, et al. Chem Biol. 2015 Jun 18;22(6):712-23. doi: 10.1016/j.chembiol.2015.04.020. Epub 2015 Jun 4. Chem Biol. 2015. PMID: 26051216 Free PMC article.

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