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Connexin 43 enhances paclitaxel cytotoxicity in colorectal cancer cell lines.
Wang S, Zhang S, Zhao Z, Zhang C, Yang X, Wang Y. Wang S, et al. Exp Ther Med. 2017 Aug;14(2):1212-1218. doi: 10.3892/etm.2017.4589. Epub 2017 Jun 13. Exp Ther Med. 2017. PMID: 28810580 Free PMC article.
Colorectal cancer has a relatively low sensitivity to paclitaxel. The purpose of this study was to investigate the role of connexin 43 (Cx43), which is a structural component of gap junctional communication (GJC), in paclitaxel cytotox
Colorectal cancer has a relatively low sensitivity to paclitaxel. The purpose of this study was to investigate the role
Kanglaite sensitizes colorectal cancer cells to Taxol via NF-kappabeta inhibition and connexin 43 upregulation.
Wang Y, Zhang C, Zhang S, Zhao Z, Wang J, Song J, Wang Y, Liu J, Hou S. Wang Y, et al. Sci Rep. 2017 Apr 28;7(1):1280. doi: 10.1038/s41598-017-01480-2. Sci Rep. 2017. PMID: 28455529 Free PMC article.
Taxol, a first-line anti-tumour drug, has low effectiveness against colorectal cancer. Combination with other agents is an effective strategy to enhance Taxol cytotoxicity. Kanglaite injection is an extract from Coix lacryma-jobi seed and is usu …
Taxol, a first-line anti-tumour drug, has low effectiveness against colorectal cancer. Combination with other agents is …