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Synthesis and structure-activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-molecule antagonists for interleukin-8 receptor.
Li JJ, Carson KG, Trivedi BK, Yue WS, Ye Q, Glynn RA, Miller SR, Connor DT, Roth BD, Luly JR, Low JE, Heilig DJ, Yang W, Qin S, Hunt S. Li JJ, et al. Among authors: connor dt. Bioorg Med Chem. 2003 Aug 15;11(17):3777-90. doi: 10.1016/s0968-0896(03)00399-7. Bioorg Med Chem. 2003. PMID: 12901923
2,6-di-tert-butylphenols: a new class of potent and selective PGHS-2 inhibitor.
Song Y, Connor DT, Sorenson RJ, Doubleday R, Sercel AD, Unangst PC, Gilbertsen RB, Chan K, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: connor dt. Inflamm Res. 1997 Aug;46 Suppl 2:S141-2. doi: 10.1007/s000110050145. Inflamm Res. 1997. PMID: 9297551 No abstract available.
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Song Y, Connor DT, Doubleday R, Sorenson RJ, Sercel AD, Unangst PC, Roth BD, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: connor dt. J Med Chem. 1999 Apr 8;42(7):1151-60. doi: 10.1021/jm9805081. J Med Chem. 1999. PMID: 10197959
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
Song Y, Connor DT, Sercel AD, Sorenson RJ, Doubleday R, Unangst PC, Roth BD, Beylin VG, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: connor dt. J Med Chem. 1999 Apr 8;42(7):1161-9. doi: 10.1021/jm980570y. J Med Chem. 1999. PMID: 10197960
(Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents.
Unangst PC, Capiris T, Connor DT, Doubleday R, Heffner TG, MacKenzie RG, Miller SR, Pugsley TA, Wise LD. Unangst PC, et al. Among authors: connor dt. J Med Chem. 1997 Dec 5;40(25):4026-9. doi: 10.1021/jm970422s. J Med Chem. 1997. PMID: 9406594
Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.
Unangst PC, Capiris T, Connor DT, Heffner TG, MacKenzie RG, Miller SR, Pugsley TA, Wise LD. Unangst PC, et al. Among authors: connor dt. J Med Chem. 1997 Aug 15;40(17):2688-93. doi: 10.1021/jm970170v. J Med Chem. 1997. PMID: 9276014
Hydroxylamine analogs of 2,6-di-t-butylphenols: dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors.
Kramer JB, Capiris T, Sircar JC, Connor DT, Bornemeier DA, Dyer RD, Kuipers PJ, Kennedy JA, Wright CD, Okonkwo GC, et al. Kramer JB, et al. Among authors: connor dt. Bioorg Med Chem. 1995 Apr;3(4):403-10. doi: 10.1016/0968-0896(95)00027-e. Bioorg Med Chem. 1995. PMID: 8581424
1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.
Boschelli DH, Connor DT, Bornemeier DA, Dyer RD, Kennedy JA, Kuipers PJ, Okonkwo GC, Schrier DJ, Wright CD. Boschelli DH, et al. Among authors: connor dt. J Med Chem. 1993 Jun 25;36(13):1802-10. doi: 10.1021/jm00065a002. J Med Chem. 1993. PMID: 8515419
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