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113 results
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The platform trial: an efficient strategy for evaluating multiple treatments.
Berry SM, Connor JT, Lewis RJ. Berry SM, et al. JAMA. 2015 Apr 28;313(16):1619-20. doi: 10.1001/jama.2015.2316. JAMA. 2015. PMID: 25799162 No abstract available.
Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication.
Lewis RJ, Connor JT, Teerlink JR, Murphy JR, Cooper LT, Hiatt WR, Brass EP. Lewis RJ, et al. Trials. 2011 May 25;12:134. doi: 10.1186/1745-6215-12-134. Trials. 2011. PMID: 21612611 Free PMC article. Clinical Trial.
An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project.
Meurer WJ, Lewis RJ, Tagle D, Fetters MD, Legocki L, Berry S, Connor J, Durkalski V, Elm J, Zhao W, Frederiksen S, Silbergleit R, Palesch Y, Berry DA, Barsan WG. Meurer WJ, et al. Ann Emerg Med. 2012 Oct;60(4):451-7. doi: 10.1016/j.annemergmed.2012.01.020. Epub 2012 Mar 15. Ann Emerg Med. 2012. PMID: 22424650 Free PMC article.
Combining risk difference and risk ratio in noninferiority trials of safety.
Broglio KR, Connor JT, Berry SM. Broglio KR, et al. J Biopharm Stat. 2013;23(1):261-71. doi: 10.1080/10543406.2011.616966. J Biopharm Stat. 2013. PMID: 23331235
Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus.
Connor JT, Elm JJ, Broglio KR; ESETT and ADAPT-IT Investigators. Connor JT, et al. J Clin Epidemiol. 2013 Aug;66(8 Suppl):S130-7. doi: 10.1016/j.jclinepi.2013.02.015. J Clin Epidemiol. 2013. PMID: 23849147 Free PMC article. Clinical Trial.
Not too big, not too small: a goldilocks approach to sample size selection.
Broglio KR, Connor JT, Berry SM. Broglio KR, et al. J Biopharm Stat. 2014;24(3):685-705. doi: 10.1080/10543406.2014.888569. J Biopharm Stat. 2014. PMID: 24697532
Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process.
Viele K, Connor JT. Viele K, et al. JAMA. 2015 Dec 1;314(21):2294-5. doi: 10.1001/jama.2015.16702. JAMA. 2015. PMID: 26624828 No abstract available.
Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design.
Lee RJ, Lakkireddy D, Mittal S, Ellis C, Connor JT, Saville BR, Wilber D. Lee RJ, et al. Am Heart J. 2015 Dec;170(6):1184-94. doi: 10.1016/j.ahj.2015.09.019. Epub 2015 Oct 3. Am Heart J. 2015. PMID: 26678640 Clinical Trial.
Using Bayesian Adaptive Trial Designs for Comparative Effectiveness Research: A Virtual Trial Execution.
Luce BR, Connor JT, Broglio KR, Mullins CD, Ishak KJ, Saunders E, Davis BR; RE-ADAPT (REsearch in ADAptive methods for Pragmatic Trials) Investigators. Luce BR, et al. Ann Intern Med. 2016 Sep 20;165(6):431-8. doi: 10.7326/M15-0823. Epub 2016 Jun 7. Ann Intern Med. 2016. PMID: 27273013
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