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Structure-based design of potent retinoid X receptor alpha agonists.
Haffner CD, Lenhard JM, Miller AB, McDougald DL, Dwornik K, Ittoop OR, Gampe RT Jr, Xu HE, Blanchard S, Montana VG, Consler TG, Bledsoe RK, Ayscue A, Croom D. Haffner CD, et al. Among authors: consler tg. J Med Chem. 2004 Apr 8;47(8):2010-29. doi: 10.1021/jm030565g. J Med Chem. 2004. PMID: 15056000
Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.
Leesnitzer LM, Parks DJ, Bledsoe RK, Cobb JE, Collins JL, Consler TG, Davis RG, Hull-Ryde EA, Lenhard JM, Patel L, Plunket KD, Shenk JL, Stimmel JB, Therapontos C, Willson TM, Blanchard SG. Leesnitzer LM, et al. Among authors: consler tg. Biochemistry. 2002 May 28;41(21):6640-50. doi: 10.1021/bi0159581. Biochemistry. 2002. PMID: 12022867
Bile acids: natural ligands for an orphan nuclear receptor.
Parks DJ, Blanchard SG, Bledsoe RK, Chandra G, Consler TG, Kliewer SA, Stimmel JB, Willson TM, Zavacki AM, Moore DD, Lehmann JM. Parks DJ, et al. Among authors: consler tg. Science. 1999 May 21;284(5418):1365-8. doi: 10.1126/science.284.5418.1365. Science. 1999. PMID: 10334993
The formation of a covalent complex between a dipeptide ligand and the src SH2 domain.
Alligood KJ, Charifson PS, Crosby R, Consler TG, Feldman PL, Gampe RT Jr, Gilmer TM, Jordan SR, Milstead MW, Mohr C, Peel MR, Rocque W, Rodriguez M, Rusnak DW, Shewchuk LM, Sternbach DD. Alligood KJ, et al. Among authors: consler tg. Bioorg Med Chem Lett. 1998 May 19;8(10):1189-94. doi: 10.1016/s0960-894x(98)00195-4. Bioorg Med Chem Lett. 1998. PMID: 9871733
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Spencer TA, Li D, Russel JS, Collins JL, Bledsoe RK, Consler TG, Moore LB, Galardi CM, McKee DD, Moore JT, Watson MA, Parks DJ, Lambert MH, Willson TM. Spencer TA, et al. Among authors: consler tg. J Med Chem. 2001 Mar 15;44(6):886-97. doi: 10.1021/jm0004749. J Med Chem. 2001. PMID: 11300870
36 results