Contestabile A - Search Results

1

Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome.

Deidda G, Parrini M, Naskar S, Bozarth IF, Contestabile A, Cancedda L. Deidda G, et al. Among authors: contestabile a. Nat Med. 2015 Apr;21(4):318-26. doi: 10.1038/nm.3827. Epub 2015 Mar 16. Nat Med. 2015. PMID: 25774849

2

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

Contestabile A, Greco B, Ghezzi D, Tucci V, Benfenati F, Gasparini L. Contestabile A, et al. J Clin Invest. 2013 Jan;123(1):348-61. doi: 10.1172/JCI64650. Epub 2012 Dec 3. J Clin Invest. 2013. PMID: 23202733 Free PMC article.

3

Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1.

Bony G, Szczurkowska J, Tamagno I, Shelly M, Contestabile A, Cancedda L. Bony G, et al. Among authors: contestabile a. Nat Commun. 2013;4:1800. doi: 10.1038/ncomms2820. Nat Commun. 2013. PMID: 23653212 Free article.

4

The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model.

Valenti D, de Bari L, de Rasmo D, Signorile A, Henrion-Caude A, Contestabile A, Vacca RA. Valenti D, et al. Among authors: contestabile a. Biochim Biophys Acta. 2016 Jun;1862(6):1093-104. doi: 10.1016/j.bbadis.2016.03.003. Epub 2016 Mar 7. Biochim Biophys Acta. 2016. PMID: 26964795 Free article.

5

The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome.

Contestabile A, Magara S, Cancedda L. Contestabile A, et al. Front Cell Neurosci. 2017 Mar 7;11:54. doi: 10.3389/fncel.2017.00054. eCollection 2017. Front Cell Neurosci. 2017. PMID: 28326014 Free PMC article. Review.

6

Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome.

Parrini M, Ghezzi D, Deidda G, Medrihan L, Castroflorio E, Alberti M, Baldelli P, Cancedda L, Contestabile A. Parrini M, et al. Among authors: contestabile a. Sci Rep. 2017 Dec 4;7(1):16825. doi: 10.1038/s41598-017-17201-8. Sci Rep. 2017. PMID: 29203796 Free PMC article.

7

A light-gated potassium channel for sustained neuronal inhibition.

Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A. Alberio L, et al. Among authors: contestabile a. Nat Methods. 2018 Nov;15(11):969-976. doi: 10.1038/s41592-018-0186-9. Epub 2018 Oct 30. Nat Methods. 2018. PMID: 30377377 Free PMC article.

8

Gene Editing Preserves Visual Functions in a Mouse Model of Retinal Degeneration.

Vagni P, Perlini LE, Chenais NAL, Marchetti T, Parrini M, Contestabile A, Cancedda L, Ghezzi D. Vagni P, et al. Among authors: contestabile a. Front Neurosci. 2019 Sep 10;13:945. doi: 10.3389/fnins.2019.00945. eCollection 2019. Front Neurosci. 2019. PMID: 31551698 Free PMC article.

9

Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders.

Savardi A, Borgogno M, Narducci R, La Sala G, Ortega JA, Summa M, Armirotti A, Bertorelli R, Contestabile A, De Vivo M, Cancedda L. Savardi A, et al. Among authors: contestabile a. Chem. 2020 Aug 6;6(8):2073-2096. doi: 10.1016/j.chempr.2020.06.017. Chem. 2020. PMID: 32818158 Free PMC article.

10

Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome.

Pinto B, Morelli G, Rastogi M, Savardi A, Fumagalli A, Petretto A, Bartolucci M, Varea E, Catelani T, Contestabile A, Perlini LE, Cancedda L. Pinto B, et al. Among authors: contestabile a. Neuron. 2020 Dec 9;108(5):887-904.e12. doi: 10.1016/j.neuron.2020.09.010. Epub 2020 Oct 6. Neuron. 2020. PMID: 33027640 Free PMC article.

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