Cook PC - Search Results

1

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, Svedberg FR, MacDonald AS, Maciewicz RA, Singh D, Hussell T. Fujimori T, et al. Among authors: cook pc. Mucosal Immunol. 2015 Sep;8(5):1021-1030. doi: 10.1038/mi.2014.129. Epub 2015 Jan 21. Mucosal Immunol. 2015. PMID: 25603826 Free PMC article.

2

CD11c depletion severely disrupts Th2 induction and development in vivo.

Phythian-Adams AT, Cook PC, Lundie RJ, Jones LH, Smith KA, Barr TA, Hochweller K, Anderton SM, Hämmerling GJ, Maizels RM, MacDonald AS. Phythian-Adams AT, et al. Among authors: cook pc. J Exp Med. 2010 Sep 27;207(10):2089-96. doi: 10.1084/jem.20100734. Epub 2010 Sep 6. J Exp Med. 2010. PMID: 20819926 Free PMC article.

3

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation.

Jenkins SJ, Ruckerl D, Cook PC, Jones LH, Finkelman FD, van Rooijen N, MacDonald AS, Allen JE. Jenkins SJ, et al. Among authors: cook pc. Science. 2011 Jun 10;332(6035):1284-8. doi: 10.1126/science.1204351. Epub 2011 May 12. Science. 2011. PMID: 21566158 Free PMC article.

4

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo.

Cook PC, Jones LH, Jenkins SJ, Wynn TA, Allen JE, MacDonald AS. Cook PC, et al. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9977-82. doi: 10.1073/pnas.1121231109. Epub 2012 Jun 1. Proc Natl Acad Sci U S A. 2012. PMID: 22660926 Free PMC article.

5

A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.

Deaton AM, Cook PC, De Sousa D, Phythian-Adams AT, Bird A, MacDonald AS. Deaton AM, et al. Among authors: cook pc. Eur J Immunol. 2014 Jun;44(6):1835-41. doi: 10.1002/eji.201344098. Epub 2014 Mar 25. Eur J Immunol. 2014. PMID: 24578067 Free PMC article.

6

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.

Morrison VL, James MJ, Grzes K, Cook P, Glass DG, Savinko T, Lek HS, Gawden-Bone C, Watts C, Millington OR, MacDonald AS, Fagerholm SC. Morrison VL, et al. Nat Commun. 2014 Oct 28;5:5359. doi: 10.1038/ncomms6359. Nat Commun. 2014. PMID: 25348463 Free PMC article.

7

Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

Jones LH, Cook PC, Ivens AC, Thomas GD, Phythian-Adams AT, Allen JE, MacDonald AS. Jones LH, et al. Among authors: cook pc. Int Immunol. 2015 Nov;27(11):589-96. doi: 10.1093/intimm/dxv020. Epub 2015 Apr 20. Int Immunol. 2015. PMID: 25899567 Free PMC article.

8

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.

Cook PC, Owen H, Deaton AM, Borger JG, Brown SL, Clouaire T, Jones GR, Jones LH, Lundie RJ, Marley AK, Morrison VL, Phythian-Adams AT, Wachter E, Webb LM, Sutherland TE, Thomas GD, Grainger JR, Selfridge J, McKenzie AN, Allen JE, Fagerholm SC, Maizels RM, Ivens AC, Bird A, MacDonald AS. Cook PC, et al. Nat Commun. 2015 Apr 24;6:6920. doi: 10.1038/ncomms7920. Nat Commun. 2015. PMID: 25908537 Free PMC article.

9

A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection.

Lundie RJ, Webb LM, Marley AK, Phythian-Adams AT, Cook PC, Jackson-Jones LH, Brown S, Maizels RM, Boon L, O'Keeffe M, MacDonald AS. Lundie RJ, et al. Among authors: cook pc. Immunol Cell Biol. 2016 Apr;94(4):400-10. doi: 10.1038/icb.2015.114. Epub 2015 Dec 11. Immunol Cell Biol. 2016. PMID: 26657145 Free PMC article.

10

Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.

Zhang X, Cook PC, Zindy E, Williams CJ, Jowitt TA, Streuli CH, MacDonald AS, Redondo-Muñoz J. Zhang X, et al. Among authors: cook pc. Nucleic Acids Res. 2016 Apr 20;44(7):3031-44. doi: 10.1093/nar/gkv1348. Epub 2015 Dec 10. Nucleic Acids Res. 2016. PMID: 26657637 Free PMC article.

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