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In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330.
Atack JR, Cook SM, Watt AP, Fletcher SR, Ragan CI. Atack JR, et al. Among authors: cook sm. J Neurochem. 1993 Feb;60(2):652-8. doi: 10.1111/j.1471-4159.1993.tb03197.x. J Neurochem. 1993. PMID: 8380439
Contribution of specific binding to the central benzodiazepine site to the brain concentrations of two novel benzodiazepine site ligands.
Pike A, Cook SM, Watt AP, Scott-Stevens P, Rosahl TW, McKernan RM, Pym LJ, Guiblin A, Moyes C, Sohal B, Atack JR. Pike A, et al. Among authors: cook sm. Biopharm Drug Dispos. 2007 Sep;28(6):275-82. doi: 10.1002/bdd.553. Biopharm Drug Dispos. 2007. PMID: 17570124
Comparison of in vivo and ex vivo [3H]flumazenil binding assays to determine occupancy at the benzodiazepine binding site of rat brain GABAA receptors.
Li J, Fish RL, Cook SM, Tattersall FD, Atack JR. Li J, et al. Among authors: cook sm. Neuropharmacology. 2006 Jul;51(1):168-72. doi: 10.1016/j.neuropharm.2006.03.020. Epub 2006 May 11. Neuropharmacology. 2006. PMID: 16697018
The in vivo properties of pagoclone in rat are most likely mediated by 5'-hydroxy pagoclone.
Atack JR, Pike A, Marshall G, Stanley J, Lincoln R, Cook SM, Lewis RT, Blackaby WP, Goodacre SC, McKernan RM, Dawson GR, Wafford KA, Reynolds DS. Atack JR, et al. Among authors: cook sm. Neuropharmacology. 2006 May;50(6):677-89. doi: 10.1016/j.neuropharm.2005.11.014. Epub 2006 Jan 20. Neuropharmacology. 2006. PMID: 16430927
Selective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513.
Pym LJ, Cook SM, Rosahl T, McKernan RM, Atack JR. Pym LJ, et al. Among authors: cook sm. Br J Pharmacol. 2005 Nov;146(6):817-25. doi: 10.1038/sj.bjp.0706392. Br J Pharmacol. 2005. PMID: 16184188 Free PMC article.
In vivo labelling of alpha5 subunit-containing GABA(A) receptors using the selective radioligand [(3)H]L-655,708.
Atack JR, Alder L, Cook SM, Smith AJ, McKernan RM. Atack JR, et al. Among authors: cook sm. Neuropharmacology. 2005 Aug;49(2):220-9. doi: 10.1016/j.neuropharm.2005.03.004. Epub 2005 Apr 26. Neuropharmacology. 2005. PMID: 15996568
Generation and characterisation of stable cell lines expressing recombinant human N-methyl-D-aspartate receptor subtypes.
Grimwood S, Le Bourdell├Ęs B, Atack JR, Barton C, Cockett W, Cook SM, Gilbert E, Hutson PH, McKernan RM, Myers J, Ragan CI, Wingrove PB, Whiting PJ. Grimwood S, et al. Among authors: cook sm. J Neurochem. 1996 Jun;66(6):2239-47. doi: 10.1046/j.1471-4159.1996.66062239.x. J Neurochem. 1996. PMID: 8632144
Measurement of lithium-induced changes in mouse inositol(1)phosphate levels in vivo.
Atack JR, Cook SM, Watt AP, Ragan CI. Atack JR, et al. Among authors: cook sm. J Neurochem. 1992 Nov;59(5):1946-54. doi: 10.1111/j.1471-4159.1992.tb11031.x. J Neurochem. 1992. PMID: 1328533
A pyridazine series of alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.
Lewis RT, Blackaby WP, Blackburn T, Jennings AS, Pike A, Wilson RA, Hallett DJ, Cook SM, Ferris P, Marshall GR, Reynolds DS, Sheppard WF, Smith AJ, Sohal B, Stanley J, Tye SJ, Wafford KA, Atack JR. Lewis RT, et al. Among authors: cook sm. J Med Chem. 2006 Apr 20;49(8):2600-10. doi: 10.1021/jm051144x. J Med Chem. 2006. PMID: 16610803
Evidence for a significant role of alpha 3-containing GABAA receptors in mediating the anxiolytic effects of benzodiazepines.
Dias R, Sheppard WF, Fradley RL, Garrett EM, Stanley JL, Tye SJ, Goodacre S, Lincoln RJ, Cook SM, Conley R, Hallett D, Humphries AC, Thompson SA, Wafford KA, Street LJ, Castro JL, Whiting PJ, Rosahl TW, Atack JR, McKernan RM, Dawson GR, Reynolds DS. Dias R, et al. Among authors: cook sm. J Neurosci. 2005 Nov 16;25(46):10682-8. doi: 10.1523/JNEUROSCI.1166-05.2005. J Neurosci. 2005. PMID: 16291941 Free PMC article.
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