Cools J - Search Results

1

Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.

Cools J, Wlodarska I, Somers R, Mentens N, Pedeutour F, Maes B, De Wolf-Peeters C, Pauwels P, Hagemeijer A, Marynen P. Cools J, et al. Genes Chromosomes Cancer. 2002 Aug;34(4):354-62. doi: 10.1002/gcc.10033. Genes Chromosomes Cancer. 2002. PMID: 12112524

2

Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia.

Peeters P, Raynaud SD, Cools J, Wlodarska I, Grosgeorge J, Philip P, Monpoux F, Van Rompaey L, Baens M, Van den Berghe H, Marynen P. Peeters P, et al. Among authors: cools j. Blood. 1997 Oct 1;90(7):2535-40. Blood. 1997. PMID: 9326218 Free article.

3

Genomic organization of human JAK2 and mutation analysis of its JH2-domain in leukemia.

Cools J, Peeters P, Voet T, Aventin A, Mecucci C, Grandchamp B, Marynen P. Cools J, et al. Cytogenet Cell Genet. 1999;85(3-4):260-6. doi: 10.1159/000015308. Cytogenet Cell Genet. 1999. PMID: 10449913

4

Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13).

Cools J, Bilhou-Nabera C, Wlodarska I, Cabrol C, Talmant P, Bernard P, Hagemeijer A, Marynen P. Cools J, et al. Blood. 1999 Sep 1;94(5):1820-4. Blood. 1999. PMID: 10477709 Free article.

5

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis.

Ma Z, Cools J, Marynen P, Cui X, Siebert R, Gesk S, Schlegelberger B, Peeters B, De Wolf-Peeters C, Wlodarska I, Morris SW. Ma Z, et al. Among authors: cools j. Blood. 2000 Mar 15;95(6):2144-9. Blood. 2000. PMID: 10706887 Free article.

6

A new family of small, palmitoylated, membrane-associated proteins, characterized by the presence of a cysteine-rich hydrophobic motif.

Cools J, Mentens N, Marynen P. Cools J, et al. FEBS Lett. 2001 Mar 16;492(3):204-9. doi: 10.1016/s0014-5793(01)02240-2. FEBS Lett. 2001. PMID: 11257495 Free article.

7

The NPM-ALK and the ATIC-ALK fusion genes can be detected in non-neoplastic cells.

Maes B, Vanhentenrijk V, Wlodarska I, Cools J, Peeters B, Marynen P, de Wolf-Peeters C. Maes B, et al. Among authors: cools j. Am J Pathol. 2001 Jun;158(6):2185-93. doi: 10.1016/S0002-9440(10)64690-1. Am J Pathol. 2001. PMID: 11395396 Free PMC article.

8

Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13).

Cools J, Mentens N, Odero MD, Peeters P, Wlodarska I, Delforge M, Hagemeijer A, Marynen P. Cools J, et al. Blood. 2002 Mar 1;99(5):1776-84. doi: 10.1182/blood.v99.5.1776. Blood. 2002. PMID: 11861295 Free article.

9

A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.

Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, Kutok J, Clark J, Galinsky I, Griffin JD, Cross NC, Tefferi A, Malone J, Alam R, Schrier SL, Schmid J, Rose M, Vandenberghe P, Verhoef G, Boogaerts M, Wlodarska I, Kantarjian H, Marynen P, Coutre SE, Stone R, Gilliland DG. Cools J, et al. N Engl J Med. 2003 Mar 27;348(13):1201-14. doi: 10.1056/NEJMoa025217. N Engl J Med. 2003. PMID: 12660384 Free article.

10

A novel cryptic translocation t(12;17)(p13;p12-p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene.

Murga Penas EM, Cools J, Algenstaedt P, Hinz K, Seeger D, Schafhausen P, Schilling G, Marynen P, Hossfeld DK, Dierlamm J. Murga Penas EM, et al. Among authors: cools j. Genes Chromosomes Cancer. 2003 May;37(1):79-83. doi: 10.1002/gcc.10175. Genes Chromosomes Cancer. 2003. PMID: 12661008

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