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Page 1
The Coombs test.
Matthews J, Newton S. Matthews J, et al. Clin J Oncol Nurs. 2010 Apr;14(2):143-5. doi: 10.1188/10.CJON.143-145. Clin J Oncol Nurs. 2010. PMID: 20350887 Review.
The Coombs test, established as a clinical tool in 1945 by R.R. Coombs, usually is ordered when hemolytic anemia is suspected or if a transfusion reaction has occurred. An overview of the etiologies of these two conditions will increase oncology nurses' under …
The Coombs test, established as a clinical tool in 1945 by R.R. Coombs, usually is ordered when hemolytic anemia is sus …
DAT-Negative Autoimmune Hemolytic Anemia.
Rodberg K. Rodberg K. Hematol Oncol Clin North Am. 2022 Apr;36(2):307-313. doi: 10.1016/j.hoc.2021.11.004. Epub 2022 Mar 10. Hematol Oncol Clin North Am. 2022. PMID: 35282952 Review.
Hematologists often rely on the results of a positive direct antiglobulin test to confirm a diagnosis of autoimmune hemolytic anemia, but immune hemolytic anemia can occur when no immunoglobulin is detectable by routine methods. ...
Hematologists often rely on the results of a positive direct antiglobulin test to confirm a diagnosis of autoimmune hemolytic anemia, …
The Direct Antiglobulin Test: Indications, Interpretation, and Pitfalls.
Parker V, Tormey CA. Parker V, et al. Arch Pathol Lab Med. 2017 Feb;141(2):305-310. doi: 10.5858/arpa.2015-0444-RS. Arch Pathol Lab Med. 2017. PMID: 28134589 Free article. Review.
The direct antiglobulin test (DAT; sometimes referred to as the "Coombs" test) continues to be one of the most widely used assays in laboratory medicine. ...The overall objective of our review is to provide practicing pathologists with a guide to identify sit …
The direct antiglobulin test (DAT; sometimes referred to as the "Coombs" test) continues to be one of the most widely u …
Coombs' testing and its diagnostic significance in dogs and cats.
Wardrop KJ. Wardrop KJ. Vet Clin North Am Small Anim Pract. 2012 Jan;42(1):43-51. doi: 10.1016/j.cvsm.2011.09.005. Epub 2011 Nov 23. Vet Clin North Am Small Anim Pract. 2012. PMID: 22285156 Review.
The Coombs' test can detect both immunoglobulin and complement on the surface of RBCs, and as such can be of value as an aid in the diagnosis of IMHA. ...
The Coombs' test can detect both immunoglobulin and complement on the surface of RBCs, and as such can be of value as an aid i …
Direct antiglobulin ("Coombs") test-negative autoimmune hemolytic anemia: a review.
Segel GB, Lichtman MA. Segel GB, et al. Blood Cells Mol Dis. 2014 Apr;52(4):152-60. doi: 10.1016/j.bcmd.2013.12.003. Epub 2014 Jan 9. Blood Cells Mol Dis. 2014. PMID: 24411920 Review.
We have reviewed the literature to identify and characterize reports of warm-antibody type, autoimmune hemolytic anemia in which the standard direct antiglobulin reaction was negative but a confirmatory test indicated that the red cells were opsonized with antibody. Three …
We have reviewed the literature to identify and characterize reports of warm-antibody type, autoimmune hemolytic anemia in which the standar …
ABO hemolytic disease of the newborn: a need for clarity and consistency in diagnosis.
Watchko JF. Watchko JF. J Perinatol. 2023 Feb;43(2):242-247. doi: 10.1038/s41372-022-01556-6. Epub 2022 Nov 8. J Perinatol. 2023. PMID: 36344813 Review.
Data on hemolysis indexed by carbon monoxide (CO) levels in expired air (ETCOc) and blood (COHbc) support an essential role for a positive direct antiglobulin test (DAT) in making a more precise diagnosis of ABO HDN. A working definition that includes ABO incompatibility, …
Data on hemolysis indexed by carbon monoxide (CO) levels in expired air (ETCOc) and blood (COHbc) support an essential role for a positive d …
The significance of antiglobulin (Coombs) test reactivity in patients with COVID-19.
Hafez W, Ziade MA, Arya A, Saleh H, Abdelrahman A. Hafez W, et al. Immunobiology. 2022 Jul;227(4):152240. doi: 10.1016/j.imbio.2022.152240. Epub 2022 Jul 6. Immunobiology. 2022. PMID: 35839729 Free PMC article.
Previous case reports have described patients with COVID-19-associated autoimmune hemolytic anemia (AIHA), and cold agglutinin disease (CAD) which is characterized by a positive direct antiglobulin (DAT) or "Coombs" test, yet the mechanism is not well understood. To …
Previous case reports have described patients with COVID-19-associated autoimmune hemolytic anemia (AIHA), and cold agglutinin disease (CAD) …
Coombs' (antiglobulin) test.
Bove JR. Bove JR. JAMA. 1967 May 8;200(6):459. JAMA. 1967. PMID: 6071612 No abstract available.
The Coombs' test in veterinary medicine: past, present, future.
Wardrop KJ. Wardrop KJ. Vet Clin Pathol. 2005 Dec;34(4):325-34. doi: 10.1111/j.1939-165x.2005.tb00057.x. Vet Clin Pathol. 2005. PMID: 16270256 Review.
The Coombs' test, also known as the antiglobulin test, is used most frequently in veterinary medicine as an aid in the diagnosis of immune-mediated hemolytic anemia. The test also is used widely in human medicine to screen for red blood cell alloantibo …
The Coombs' test, also known as the antiglobulin test, is used most frequently in veterinary medicine as an aid in the …
Professor Robin Coombs FRS (1921-2006).
Kay AB. Kay AB. Vox Sang. 2006 Aug;91(2):93-4. doi: 10.1111/j.1423-0410.2006.00811.x. Vox Sang. 2006. PMID: 16907867 No abstract available.
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