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47 results
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Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death.
Haynes CM, Titus EA, Cooper AA. Haynes CM, et al. Among authors: cooper aa. Mol Cell. 2004 Sep 10;15(5):767-76. doi: 10.1016/j.molcel.2004.08.025. Mol Cell. 2004. PMID: 15350220
ERADicate ER stress or die trying.
Kincaid MM, Cooper AA. Kincaid MM, et al. Among authors: cooper aa. Antioxid Redox Signal. 2007 Dec;9(12):2373-87. doi: 10.1089/ars.2007.1817. Antioxid Redox Signal. 2007. PMID: 17883326 Review.
Misfolded proteins traffic from the endoplasmic reticulum (ER) due to ER export signals.
Kincaid MM, Cooper AA. Kincaid MM, et al. Among authors: cooper aa. Mol Biol Cell. 2007 Feb;18(2):455-63. doi: 10.1091/mbc.e06-08-0696. Epub 2006 Nov 15. Mol Biol Cell. 2007. PMID: 17108324 Free PMC article.
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, Labaer J, Rochet JC, Bonini NM, Lindquist S. Cooper AA, et al. Science. 2006 Jul 21;313(5785):324-8. doi: 10.1126/science.1129462. Epub 2006 Jun 22. Science. 2006. PMID: 16794039 Free PMC article.
An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport.
Haynes CM, Caldwell S, Cooper AA. Haynes CM, et al. Among authors: cooper aa. J Cell Biol. 2002 Jul 8;158(1):91-101. doi: 10.1083/jcb.200201053. Epub 2002 Jul 8. J Cell Biol. 2002. PMID: 12105183 Free PMC article.
Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases.
Cooper AA, Stevens TH. Cooper AA, et al. J Cell Biol. 1996 May;133(3):529-41. doi: 10.1083/jcb.133.3.529. J Cell Biol. 1996. PMID: 8636229 Free PMC article.
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae.
Piper RC, Cooper AA, Yang H, Stevens TH. Piper RC, et al. Among authors: cooper aa. J Cell Biol. 1995 Nov;131(3):603-17. doi: 10.1083/jcb.131.3.603. J Cell Biol. 1995. PMID: 7593183 Free PMC article.
Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system.
Hill K, Cooper AA. Hill K, et al. Among authors: cooper aa. EMBO J. 2000 Feb 15;19(4):550-61. doi: 10.1093/emboj/19.4.550. EMBO J. 2000. PMID: 10675324 Free PMC article.
Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi.
Caldwell SR, Hill KJ, Cooper AA. Caldwell SR, et al. Among authors: cooper aa. J Biol Chem. 2001 Jun 29;276(26):23296-303. doi: 10.1074/jbc.M102962200. Epub 2001 Apr 20. J Biol Chem. 2001. PMID: 11316816
Protein splicing: excision of intervening sequences at the protein level.
Cooper AA, Stevens TH. Cooper AA, et al. Bioessays. 1993 Oct;15(10):667-74. doi: 10.1002/bies.950151006. Bioessays. 1993. PMID: 8274142 Review.
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