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31 results
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Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity.
Diallo H, Angell DC, Barnett HA, Biggadike K, Coe DM, Cooper TW, Craven A, Gray JR, House D, Jack TI, Keeling SP, Macdonald SJ, McLay IM, Oliver S, Taylor SJ, Uings IJ, Wellaway N. Diallo H, et al. Among authors: cooper tw. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1126-33. doi: 10.1016/j.bmcl.2010.12.121. Epub 2010 Dec 31. Bioorg Med Chem Lett. 2011. PMID: 21257309
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor.
Biggadike K, Bledsoe RK, Coe DM, Cooper TW, House D, Iannone MA, Macdonald SJ, Madauss KP, McLay IM, Shipley TJ, Taylor SJ, Tran TB, Uings IJ, Weller V, Williams SP. Biggadike K, et al. Among authors: cooper tw. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18114-9. doi: 10.1073/pnas.0909125106. Epub 2009 Oct 12. Proc Natl Acad Sci U S A. 2009. PMID: 19822747 Free PMC article.
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists.
Barnett HA, Coe DM, Cooper TW, Jack TI, Jones HT, Macdonald SJ, McLay IM, Rayner N, Sasse RZ, Shipley TJ, Skone PA, Somers GI, Taylor S, Uings IJ, Woolven JM, Weingarten GG. Barnett HA, et al. Among authors: cooper tw. Bioorg Med Chem Lett. 2009 Jan 1;19(1):158-62. doi: 10.1016/j.bmcl.2008.10.128. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19019676
High recurrence rate of CA-MRSA skin and soft tissue infections.
Skiest DJ, Cooper TW. Skiest DJ, et al. Among authors: cooper tw. Arch Intern Med. 2007 Dec 10;167(22):2527author reply 2527. doi: 10.1001/archinte.167.22.2527-a. Arch Intern Med. 2007. PMID: 18071179 No abstract available.
Part X. Tetracycline and glycylcycline antimicrobials.
Vincent S, Bronze MS, Cooper TW, Greenfied RA. Vincent S, et al. Among authors: cooper tw. J Okla State Med Assoc. 2007 Jun;100(6):241-7. J Okla State Med Assoc. 2007. PMID: 17708423 Review. No abstract available.
Part IX. Quinolone antimicrobials.
Vincent S, Machado L, Cooper TW, Bronze MS, Greenfield RA. Vincent S, et al. Among authors: cooper tw. J Okla State Med Assoc. 2007 May;100(5):149-56. J Okla State Med Assoc. 2007. PMID: 17557602 Review. No abstract available.
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