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Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559).
Hotchkiss RS, Colston E, Yende S, Angus DC, Moldawer LL, Crouser ED, Martin GS, Coopersmith CM, Brakenridge S, Mayr FB, Park PK, Ye J, Catlett IM, Girgis IG, Grasela DM. Hotchkiss RS, et al. Among authors: coopersmith cm. Crit Care Med. 2019 May;47(5):632-642. doi: 10.1097/CCM.0000000000003685. Crit Care Med. 2019. PMID: 30747773 Free PMC article. Clinical Trial.
High-dose exogenous iron following cecal ligation and puncture increases mortality rate in mice and is associated with an increase in gut epithelial and splenic apoptosis.
Javadi P, Buchman TG, Stromberg PE, Husain KD, Dunne WM, Woolsey CA, Turnbull IR, Hotchkiss RS, Karl IE, Coopersmith CM. Javadi P, et al. Among authors: coopersmith cm. Crit Care Med. 2004 May;32(5):1178-85. doi: 10.1097/01.ccm.0000124878.02614.4c. Crit Care Med. 2004. PMID: 15190970
271 results