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Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction.
Gaspar HB, Cooray S, Gilmour KC, Parsley KL, Zhang F, Adams S, Bjorkegren E, Bayford J, Brown L, Davies EG, Veys P, Fairbanks L, Bordon V, Petropoulou T, Kinnon C, Thrasher AJ. Gaspar HB, et al. Among authors: cooray s. Sci Transl Med. 2011 Aug 24;3(97):97ra80. doi: 10.1126/scitranslmed.3002716. Sci Transl Med. 2011. PMID: 21865538 Clinical Trial.
Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence.
Maluquer de Motes C, Cooray S, Ren H, Almeida GM, McGourty K, Bahar MW, Stuart DI, Grimes JM, Graham SC, Smith GL. Maluquer de Motes C, et al. Among authors: cooray s. PLoS Pathog. 2011 Dec;7(12):e1002430. doi: 10.1371/journal.ppat.1002430. Epub 2011 Dec 15. PLoS Pathog. 2011. PMID: 22194685 Free PMC article.
How vaccinia virus has evolved to subvert the host immune response.
Bahar MW, Graham SC, Chen RA, Cooray S, Smith GL, Stuart DI, Grimes JM. Bahar MW, et al. Among authors: cooray s. J Struct Biol. 2011 Aug;175(2):127-34. doi: 10.1016/j.jsb.2011.03.010. Epub 2011 Mar 17. J Struct Biol. 2011. PMID: 21419849 Free PMC article. Review.
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