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Modulation of the W748S mutation in DNA polymerase gamma by the E1143G polymorphismin mitochondrial disorders.
Chan SS, Longley MJ, Copeland WC. Chan SS, et al. Among authors: copeland wc. Hum Mol Genet. 2006 Dec 1;15(23):3473-83. doi: 10.1093/hmg/ddl424. Epub 2006 Nov 6. Hum Mol Genet. 2006. PMID: 17088268 Free PMC article.
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis.
Ponamarev MV, Longley MJ, Nguyen D, Kunkel TA, Copeland WC. Ponamarev MV, et al. Among authors: copeland wc. J Biol Chem. 2002 May 3;277(18):15225-8. doi: 10.1074/jbc.C200100200. Epub 2002 Mar 15. J Biol Chem. 2002. PMID: 11897778
Measuring mtDNA mutation rates in Saccharomyces cerevisiae using the mtArg8 assay.
Strand MK, Copeland WC. Strand MK, et al. Among authors: copeland wc. Methods Mol Biol. 2002;197:151-7. doi: 10.1385/1-59259-284-8:151. Methods Mol Biol. 2002. PMID: 12013793 No abstract available.
Purification, separation, and identification of the human mtDNA polymerase with and without its accessory subunit.
Longley MJ, Copeland WC. Longley MJ, et al. Among authors: copeland wc. Methods Mol Biol. 2002;197:245-57. doi: 10.1385/1-59259-284-8:245. Methods Mol Biol. 2002. PMID: 12013800 No abstract available.
Base composition at mtDNA boundaries suggests a DNA triple helix model for human mitochondrial DNA large-scale rearrangements.
Rocher C, Letellier T, Copeland WC, Lestienne P. Rocher C, et al. Among authors: copeland wc. Mol Genet Metab. 2002 Jun;76(2):123-32. doi: 10.1016/s1096-7192(02)00024-0. Mol Genet Metab. 2002. PMID: 12083809
The mitochondrial DNA polymerase as a target of oxidative damage.
Graziewicz MA, Day BJ, Copeland WC. Graziewicz MA, et al. Among authors: copeland wc. Nucleic Acids Res. 2002 Jul 1;30(13):2817-24. doi: 10.1093/nar/gkf392. Nucleic Acids Res. 2002. PMID: 12087165 Free PMC article.
Mitochondrial DNA alterations in cancer.
Copeland WC, Wachsman JT, Johnson FM, Penta JS. Copeland WC, et al. Cancer Invest. 2002;20(4):557-69. doi: 10.1081/cnv-120002155. Cancer Invest. 2002. PMID: 12094550 Review.
Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders.
Copeland WC, Ponamarev MV, Nguyen D, Kunkel TA, Longley MJ. Copeland WC, et al. Acta Biochim Pol. 2003;50(1):155-67. Acta Biochim Pol. 2003. PMID: 12673356 Review.
Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.
Lim SE, Ponamarev MV, Longley MJ, Copeland WC. Lim SE, et al. Among authors: copeland wc. J Mol Biol. 2003 May 23;329(1):45-57. doi: 10.1016/s0022-2836(03)00405-4. J Mol Biol. 2003. PMID: 12742017
DNA polymerase gamma in mitochondrial DNA replication and repair.
Copeland WC, Longley MJ. Copeland WC, et al. ScientificWorldJournal. 2003 Mar 17;3:34-44. doi: 10.1100/tsw.2003.09. ScientificWorldJournal. 2003. PMID: 12806118 Free PMC article. Review.
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