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PD-L1 blockade enhances anti-tumor efficacy of NK cells.

Oyer JL, Gitto SB, Altomare DA, Copik AJ. Oyer JL, et al. Among authors: copik aj. Oncoimmunology. 2018 Aug 27;7(11):e1509819. doi: 10.1080/2162402X.2018.1509819. eCollection 2018. Oncoimmunology. 2018. PMID: 30377572 Free PMC article.

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Combination Therapy with c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells.

Fuse MA, Plati SK, Burns SS, Dinh CT, Bracho O, Yan D, Mittal R, Shen R, Soulakova JN, Copik AJ, Liu XZ, Telischi FF, Chang LS, Franco MC, Fernandez-Valle C. Fuse MA, et al. Among authors: copik aj. Mol Cancer Ther. 2017 Nov;16(11):2387-2398. doi: 10.1158/1535-7163.MCT-17-0417. Epub 2017 Aug 3. Mol Cancer Ther. 2017. PMID: 28775147

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Cytokines in immunogenic cell death: Applications for cancer immunotherapy.

Showalter A, Limaye A, Oyer JL, Igarashi R, Kittipatarin C, Copik AJ, Khaled AR. Showalter A, et al. Among authors: copik aj. Cytokine. 2017 Sep;97:123-132. doi: 10.1016/j.cyto.2017.05.024. Epub 2017 Jun 22. Cytokine. 2017. PMID: 28648866 Free PMC article. Review.

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Natural killer cells stimulated with PM21 particles expand and biodistribute in vivo: Clinical implications for cancer treatment.

Oyer JL, Pandey V, Igarashi RY, Somanchi SS, Zakari A, Solh M, Lee DA, Altomare DA, Copik AJ. Oyer JL, et al. Among authors: copik aj. Cytotherapy. 2016 May;18(5):653-63. doi: 10.1016/j.jcyt.2016.02.006. Cytotherapy. 2016. PMID: 27059202

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Generation of highly cytotoxic natural killer cells for treatment of acute myelogenous leukemia using a feeder-free, particle-based approach.

Oyer JL, Igarashi RY, Kulikowski AR, Colosimo DA, Solh MM, Zakari A, Khaled YA, Altomare DA, Copik AJ. Oyer JL, et al. Among authors: copik aj. Biol Blood Marrow Transplant. 2015 Apr;21(4):632-9. doi: 10.1016/j.bbmt.2014.12.037. Epub 2015 Jan 6. Biol Blood Marrow Transplant. 2015. PMID: 25576425

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Anti-ovarian tumor response of donor peripheral blood mononuclear cells is due to infiltrating cytotoxic NK cells.

Pandey V, Oyer JL, Igarashi RY, Gitto SB, Copik AJ, Altomare DA. Pandey V, et al. Among authors: copik aj. Oncotarget. 2016 Feb 9;7(6):7318-28. doi: 10.18632/oncotarget.6939. Oncotarget. 2016. PMID: 26802025 Free PMC article.

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Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.

Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C. Fuse MA, et al. Among authors: copik aj. Neuro Oncol. 2019 Mar 18;21(4):486-497. doi: 10.1093/neuonc/noz002. Neuro Oncol. 2019. PMID: 30615146 Free PMC article.

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Difluoromethylornithine Combined with a Polyamine Transport Inhibitor Is Effective against Gemcitabine Resistant Pancreatic Cancer.

Gitto SB, Pandey V, Oyer JL, Copik AJ, Hogan FC, Phanstiel O 4th, Altomare DA. Gitto SB, et al. Among authors: copik aj. Mol Pharm. 2018 Feb 5;15(2):369-376. doi: 10.1021/acs.molpharmaceut.7b00718. Epub 2018 Jan 4. Mol Pharm. 2018. PMID: 29299930

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Development and characterization of conducting polymer nanoparticles for photodynamic therapy in vitro.

Doshi M, Copik A, Gesquiere AJ. Doshi M, et al. Among authors: copik a. Photodiagnosis Photodyn Ther. 2015 Sep;12(3):476-89. doi: 10.1016/j.pdpdt.2015.04.010. Epub 2015 May 11. Photodiagnosis Photodyn Ther. 2015. PMID: 25976507

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The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption.

Lee MW, Bassiouni R, Sparrow NA, Iketani A, Boohaker RJ, Moskowitz C, Vishnubhotla P, Khaled AS, Oyer J, Copik A, Fernandez-Valle C, Perez JM, Khaled AR. Lee MW, et al. Cell Death Dis. 2014 May 22;5(5):e1249. doi: 10.1038/cddis.2014.225. Cell Death Dis. 2014. PMID: 24853427 Free PMC article.

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