Copple BL - Search Results

1

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.

Allen K, Jaeschke H, Copple BL. Allen K, et al. Among authors: copple bl. Am J Pathol. 2011 Jan;178(1):175-86. doi: 10.1016/j.ajpath.2010.11.026. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224055 Free PMC article.

2

Early growth response factor-1 is critical for cholestatic liver injury.

Kim ND, Moon JO, Slitt AL, Copple BL. Kim ND, et al. Among authors: copple bl. Toxicol Sci. 2006 Apr;90(2):586-95. doi: 10.1093/toxsci/kfj111. Epub 2006 Jan 19. Toxicol Sci. 2006. PMID: 16423862

3

Reduced liver fibrosis in hypoxia-inducible factor-1alpha-deficient mice.

Moon JO, Welch TP, Gonzalez FJ, Copple BL. Moon JO, et al. Among authors: copple bl. Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G582-92. doi: 10.1152/ajpgi.90368.2008. Epub 2009 Jan 8. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19136383 Free PMC article.

4

Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.

Luyendyk JP, Cantor GH, Kirchhofer D, Mackman N, Copple BL, Wang R. Luyendyk JP, et al. Among authors: copple bl. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G840-9. doi: 10.1152/ajpgi.90639.2008. Epub 2009 Jan 29. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19179621 Free PMC article.

5

Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes.

Copple BL, Bustamante JJ, Welch TP, Kim ND, Moon JO. Copple BL, et al. Liver Int. 2009 Aug;29(7):1010-21. doi: 10.1111/j.1478-3231.2009.02015.x. Epub 2009 Mar 19. Liver Int. 2009. PMID: 19302442 Free PMC article.

6

Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.

Allen K, Kim ND, Moon JO, Copple BL. Allen K, et al. Among authors: copple bl. Toxicol Appl Pharmacol. 2010 Feb 15;243(1):63-7. doi: 10.1016/j.taap.2009.11.013. Epub 2009 Nov 17. Toxicol Appl Pharmacol. 2010. PMID: 19931294 Free PMC article.

7

Oxidative stress and the pathogenesis of cholestasis.

Copple BL, Jaeschke H, Klaassen CD. Copple BL, et al. Semin Liver Dis. 2010 May;30(2):195-204. doi: 10.1055/s-0030-1253228. Epub 2010 Apr 26. Semin Liver Dis. 2010. PMID: 20422501 Review.

8

Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis.

Luyendyk JP, Kassel KM, Allen K, Guo GL, Li G, Cantor GH, Copple BL. Luyendyk JP, et al. Among authors: copple bl. Am J Pathol. 2011 Mar;178(3):1117-25. doi: 10.1016/j.ajpath.2010.11.064. Am J Pathol. 2011. PMID: 21356363 Free PMC article.

9

Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes.

Mei S, Ni HM, Manley S, Bockus A, Kassel KM, Luyendyk JP, Copple BL, Ding WX. Mei S, et al. Among authors: copple bl. J Pharmacol Exp Ther. 2011 Nov;339(2):487-98. doi: 10.1124/jpet.111.184341. Epub 2011 Aug 19. J Pharmacol Exp Ther. 2011. PMID: 21856859 Free PMC article.

10

Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.

Sullivan BP, Cui W, Copple BL, Luyendyk JP. Sullivan BP, et al. Among authors: copple bl. Toxicol Sci. 2012 Mar;126(1):267-74. doi: 10.1093/toxsci/kfr311. Epub 2011 Nov 17. Toxicol Sci. 2012. PMID: 22094456 Free PMC article.

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