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Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.
Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, Ostrowski MC, Pagano M, Leone G. Cuitiño MC, et al. Among authors: coppola v. Cell Rep. 2019 Jun 18;27(12):3547-3560.e5. doi: 10.1016/j.celrep.2019.05.004. Epub 2019 May 23. Cell Rep. 2019. PMID: 31130414 Free PMC article.
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G. Caserta E, et al. Among authors: coppola v. Genes Dev. 2015 Aug 15;29(16):1707-20. doi: 10.1101/gad.262568.115. Genes Dev. 2015. PMID: 26302789 Free PMC article.
E2f8 mediates tumor suppression in postnatal liver development.
Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G. Kent LN, et al. Among authors: coppola v. J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25. J Clin Invest. 2016. PMID: 27454291 Free PMC article.
Selective targeting of point-mutated KRAS through artificial microRNAs.
Acunzo M, Romano G, Nigita G, Veneziano D, Fattore L, Laganà A, Zanesi N, Fadda P, Fassan M, Rizzotto L, Kladney R, Coppola V, Croce CM. Acunzo M, et al. Among authors: coppola v. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4203-E4212. doi: 10.1073/pnas.1620562114. Epub 2017 May 8. Proc Natl Acad Sci U S A. 2017. PMID: 28484014 Free PMC article.
Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Liu H, Dowdle JA, Khurshid S, Sullivan NJ, Bertos N, Rambani K, Mair M, Daniel P, Wheeler E, Tang X, Toth K, Lause M, Harrigan ME, Eiring K, Sullivan C, Sullivan MJ, Chang SW, Srivastava S, Conway JS, Kladney R, McElroy J, Bae S, Lu Y, Tofigh A, Saleh SMI, Fernandez SA, Parvin JD, Coppola V, Macrae ER, Majumder S, Shapiro CL, Yee LD, Ramaswamy B, Hallett M, Ostrowski MC, Park M, Chamberlin HM, Leone G. Liu H, et al. Among authors: coppola v. Dev Cell. 2017 May 22;41(4):392-407.e6. doi: 10.1016/j.devcel.2017.04.024. Dev Cell. 2017. PMID: 28535374 Free PMC article.
Emi2 Is Essential for Mouse Spermatogenesis.
Gopinathan L, Szmyd R, Low D, Diril MK, Chang HY, Coppola V, Liu K, Tessarollo L, Guccione E, van Pelt AMM, Kaldis P. Gopinathan L, et al. Among authors: coppola v. Cell Rep. 2017 Jul 18;20(3):697-708. doi: 10.1016/j.celrep.2017.06.033. Cell Rep. 2017. PMID: 28723571 Free PMC article.
POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.
Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR. Gudmundsdottir B, et al. Among authors: coppola v. Cell Rep. 2018 Jun 12;23(11):3236-3248. doi: 10.1016/j.celrep.2018.05.043. Cell Rep. 2018. PMID: 29898395 Free PMC article.
Endoreduplication of the mouse genome in the absence of ORC1.
Okano-Uchida T, Kent LN, Ouseph MM, McCarty B, Frank JJ, Kladney R, Cuitino MC, Thompson JC, Coppola V, Asano M, Leone G. Okano-Uchida T, et al. Among authors: coppola v. Genes Dev. 2018 Jul 1;32(13-14):978-990. doi: 10.1101/gad.311910.118. Genes Dev. 2018. PMID: 29967292 Free PMC article.
245 results