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Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.
Tansey KE, Rucker JJ, Kavanagh DH, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans DM, Hauser J, Henigsberg N, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Lewis G, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Pharmacogenomics J. 2014 Aug;14(4):395-9. doi: 10.1038/tpj.2013.51. Epub 2014 Jan 21. Pharmacogenomics J. 2014. PMID: 24445990
It would be beneficial to find genetic predictors of antidepressant response to help personalise treatment of major depressive disorder (MDD). Rare copy number variants (CNVs) have been implicated in several psychiatric diso …
It would be beneficial to find genetic predictors of antidepressant response to help personalise treatment of major
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.
Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM, Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I, Lewis CM, McGuffin P. Uher R, et al. Am J Psychiatry. 2010 May;167(5):555-64. doi: 10.1176/appi.ajp.2009.09070932. Epub 2010 Apr 1. Am J Psychiatry. 2010. PMID: 20360315
OBJECTIVE: The purpose of this study was to identify genetic variants underlying the considerable individual differences in response to antidepressant treatment. ...RESULTS: Single nucleotide polymorphisms in two intergenic regions containing copy n
OBJECTIVE: The purpose of this study was to identify genetic variants underlying the considerable individual differences in respon