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HIF1α and metabolic reprogramming in inflammation.
Corcoran SE, O'Neill LA. Corcoran SE, et al. J Clin Invest. 2016 Oct 3;126(10):3699-3707. doi: 10.1172/JCI84431. Epub 2016 Aug 29. J Clin Invest. 2016. PMID: 27571407 Free PMC article. Review.
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O'Neill LAJ. Hooftman A, et al. Among authors: corcoran se. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016. Epub 2020 Aug 12. Cell Metab. 2020. PMID: 32791101 Free PMC article.
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.
Early JO, Menon D, Wyse CA, Cervantes-Silva MP, Zaslona Z, Carroll RG, Palsson-McDermott EM, Angiari S, Ryan DG, Corcoran SE, Timmons G, Geiger SS, Fitzpatrick DJ, O'Connell D, Xavier RJ, Hokamp K, O'Neill LAJ, Curtis AM. Early JO, et al. Among authors: corcoran se. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8460-E8468. doi: 10.1073/pnas.1800431115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127006 Free PMC article.
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
Ní Cheallaigh C, Sheedy FJ, Harris J, Muñoz-Wolf N, Lee J, West K, McDermott EP, Smyth A, Gleeson LE, Coleman M, Martinez N, Hearnden CH, Tynan GA, Carroll EC, Jones SA, Corr SC, Bernard NJ, Hughes MM, Corcoran SE, O'Sullivan M, Fallon CM, Kornfeld H, Golenbock D, Gordon SV, O'Neill LA, Lavelle EC, Keane J. Ní Cheallaigh C, et al. Among authors: corcoran se. Immunity. 2016 Feb 16;44(2):368-79. doi: 10.1016/j.immuni.2016.01.019. Immunity. 2016. PMID: 26885859 Free PMC article.
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion.
McGettrick AF, Corcoran SE, Barry PJ, McFarland J, Crès C, Curtis AM, Franklin E, Corr SC, Mok KH, Cummins EP, Taylor CT, O'Neill LA, Nolan DP. McGettrick AF, et al. Among authors: corcoran se. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7778-E7787. doi: 10.1073/pnas.1608221113. Epub 2016 Nov 15. Proc Natl Acad Sci U S A. 2016. PMID: 27856732 Free PMC article.
MiR-155 deletion reduces ischemia-induced paralysis in an aortic aneurysm repair mouse model: Utility of immunohistochemistry and histopathology in understanding etiology of spinal cord paralysis.
Awad H, Bratasz A, Nuovo G, Burry R, Meng X, Kelani H, Brown M, Ramadan ME, Williams J, Bouhliqah L, Popovich PG, Guan Z, Mcallister C, Corcoran SE, Kaspar B, Michele Basso D, Otero JJ, Kirsch C, Davis IC, Croce CM, Michaille JJ, Tili E. Awad H, et al. Among authors: corcoran se. Ann Diagn Pathol. 2018 Oct;36:12-20. doi: 10.1016/j.anndiagpath.2018.06.002. Epub 2018 Jun 18. Ann Diagn Pathol. 2018. PMID: 29966831 Free PMC article.