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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia.
Agirre X, Vilas-Zornoza A, Jiménez-Velasco A, Martin-Subero JI, Cordeu L, Gárate L, San José-Eneriz E, Abizanda G, Rodríguez-Otero P, Fortes P, Rifón J, Bandrés E, Calasanz MJ, Martín V, Heiniger A, Torres A, Siebert R, Román-Gomez J, Prósper F. Agirre X, et al. Among authors: cordeu l. Cancer Res. 2009 May 15;69(10):4443-53. doi: 10.1158/0008-5472.CAN-08-4025. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435910 Free article.
Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth.
Agirre X, Jiménez-Velasco A, San José-Enériz E, Garate L, Bandrés E, Cordeu L, Aparicio O, Saez B, Navarro G, Vilas-Zornoza A, Pérez-Roger I, García-Foncillas J, Torres A, Heiniger A, Calasanz MJ, Fortes P, Román-Gómez J, Prósper F. Agirre X, et al. Among authors: cordeu l. Mol Cancer Res. 2008 Dec;6(12):1830-40. doi: 10.1158/1541-7786.MCR-08-0167. Mol Cancer Res. 2008. PMID: 19074828
Epigenetic regulation of microRNAs in acute lymphoblastic leukemia.
Roman-Gomez J, Agirre X, Jiménez-Velasco A, Arqueros V, Vilas-Zornoza A, Rodriguez-Otero P, Martin-Subero I, Garate L, Cordeu L, San José-Eneriz E, Martin V, Castillejo JA, Bandrés E, Calasanz MJ, Siebert R, Heiniger A, Torres A, Prosper F. Roman-Gomez J, et al. Among authors: cordeu l. J Clin Oncol. 2009 Mar 10;27(8):1316-22. doi: 10.1200/JCO.2008.19.3441. Epub 2009 Jan 21. J Clin Oncol. 2009. PMID: 19164206
Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.
San José-Eneriz E, Agirre X, Jiménez-Velasco A, Cordeu L, Martín V, Arqueros V, Gárate L, Fresquet V, Cervantes F, Martínez-Climent JA, Heiniger A, Torres A, Prósper F, Roman-Gomez J. San José-Eneriz E, et al. Among authors: cordeu l. Eur J Cancer. 2009 Jul;45(10):1877-89. doi: 10.1016/j.ejca.2009.04.005. Epub 2009 May 4. Eur J Cancer. 2009. PMID: 19403302 Free article.
Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia.
Agirre X, Román-Gómez J, Vázquez I, Jiménez-Velasco A, Garate L, Montiel-Duarte C, Artieda P, Cordeu L, Lahortiga I, Calasanz MJ, Heiniger A, Torres A, Minna JD, Prósper F. Agirre X, et al. Among authors: cordeu l. Int J Cancer. 2006 Apr 15;118(8):1945-53. doi: 10.1002/ijc.21584. Int J Cancer. 2006. PMID: 16287063 Free article.
Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia.
Román-Gómez J, Cordeu L, Agirre X, Jiménez-Velasco A, San José-Eneriz E, Garate L, Calasanz MJ, Heiniger A, Torres A, Prosper F. Román-Gómez J, et al. Among authors: cordeu l. Blood. 2007 Apr 15;109(8):3462-9. doi: 10.1182/blood-2006-09-047043. Epub 2006 Dec 5. Blood. 2007. PMID: 17148581 Free article. Retracted. Clinical Trial.
Resistance to Imatinib Mesylate-induced apoptosis in acute lymphoblastic leukemia is associated with PTEN down-regulation due to promoter hypermethylation.
Montiel-Duarte C, Cordeu L, Agirre X, Román-Gómez J, Jiménez-Velasco A, José-Eneriz ES, Gárate L, Andreu EJ, Calasanz MJ, Heiniger A, Torres A, Prósper F. Montiel-Duarte C, et al. Among authors: cordeu l. Leuk Res. 2008 May;32(5):709-16. doi: 10.1016/j.leukres.2007.09.005. Epub 2007 Oct 17. Leuk Res. 2008. PMID: 17942153
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