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2020 14
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Efficacy and safety of COVID-19 vaccines.
Graña C, Ghosn L, Evrenoglou T, Jarde A, Minozzi S, Bergman H, Buckley BS, Probyn K, Villanueva G, Henschke N, Bonnet H, Assi R, Menon S, Marti M, Devane D, Mallon P, Lelievre JD, Askie LM, Kredo T, Ferrand G, Davidson M, Riveros C, Tovey D, Meerpohl JJ, Grasselli G, Rada G, Hróbjartsson A, Ravaud P, Chaimani A, Boutron I. Graña C, et al. Cochrane Database Syst Rev. 2022 Dec 7;12(12):CD015477. doi: 10.1002/14651858.CD015477. Cochrane Database Syst Rev. 2022. PMID: 36473651 Free PMC article. Review.
SEARCH METHODS: We searched the Cochrane COVID-19 Study Register and the COVID-19 L.OVE platform (last search date 5 November 2021). ...This abstract reports results for the critical outcomes of confirmed symptomatic COVID-19, severe and …
SEARCH METHODS: We searched the Cochrane COVID-19 Study Register and the COVID-19 L.OVE platform (last search da …
Coronavirus disease 2019: Implications of emerging infections for transplantation.
Michaels MG, La Hoz RM, Danziger-Isakov L, Blumberg EA, Kumar D, Green M, Pruett TL, Wolfe CR. Michaels MG, et al. Am J Transplant. 2020 Jul;20(7):1768-1772. doi: 10.1111/ajt.15832. Epub 2020 Mar 16. Am J Transplant. 2020. PMID: 32090448 Free PMC article.
The recent identification of an outbreak of 2019- novel Coronavirus is currently evolving, and the impact on transplantation is unknown. However, it is imperative that we anticipate the potential impact on the transplant community in order to avert severe consequenc …
The recent identification of an outbreak of 2019- novel Coronavirus is currently evolving, and the impact on transplantation is unkno …
Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors.
Mazza MG, De Lorenzo R, Conte C, Poletti S, Vai B, Bollettini I, Melloni EMT, Furlan R, Ciceri F, Rovere-Querini P; COVID-19 BioB Outpatient Clinic Study group; Benedetti F. Mazza MG, et al. Brain Behav Immun. 2020 Oct;89:594-600. doi: 10.1016/j.bbi.2020.07.037. Epub 2020 Jul 30. Brain Behav Immun. 2020. PMID: 32738287 Free PMC article.
The spreading of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) pandemic could be associated with psychiatric implications. We investigated the psychopathological impact of COVID-19 in survivors, also considering the effect of clin …
The spreading of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) pandemic could be associated with psychiatric …
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.
Meng B, Abdullahi A, Ferreira IATM, Goonawardane N, Saito A, Kimura I, Yamasoba D, Gerber PP, Fatihi S, Rathore S, Zepeda SK, Papa G, Kemp SA, Ikeda T, Toyoda M, Tan TS, Kuramochi J, Mitsunaga S, Ueno T, Shirakawa K, Takaori-Kondo A, Brevini T, Mallery DL, Charles OJ; CITIID-NIHR BioResource COVID-19 Collaboration; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ecuador-COVID19 Consortium; Bowen JE, Joshi A, Walls AC, Jackson L, Martin D, Smith KGC, Bradley J, Briggs JAG, Choi J, Madissoon E, Meyer KB, Mlcochova P, Ceron-Gutierrez L, Doffinger R, Teichmann SA, Fisher AJ, Pizzuto MS, de Marco A, Corti D, Hosmillo M, Lee JH, James LC, Thukral L, Veesler D, Sigal A, Sampaziotis F, Goodfellow IG, Matheson NJ, Sato K, Gupta RK. Meng B, et al. Nature. 2022 Mar;603(7902):706-714. doi: 10.1038/s41586-022-04474-x. Epub 2022 Feb 1. Nature. 2022. PMID: 35104837 Free PMC article.
The SARS-CoV-2 Omicron BA.1 variant emerged in 2021(1) and has multiple mutations in its spike protein(2). Here we show that the spike protein of Omicron has a higher affinity for ACE2 compared with Delta, and a marked change in its antigenicity increases Omicron's evasion …
The SARS-CoV-2 Omicron BA.1 variant emerged in 2021(1) and has multiple mutations in its spike protein(2). Here we show that the spik …
Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches.
Molnar T, Lehoczki A, Fekete M, Varnai R, Zavori L, Erdo-Bonyar S, Simon D, Berki T, Csecsei P, Ezer E. Molnar T, et al. Geroscience. 2024 Oct;46(5):5267-5286. doi: 10.1007/s11357-024-01165-5. Epub 2024 Apr 26. Geroscience. 2024. PMID: 38668888 Free PMC article. Review.
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has introduced the medical community to the phenomenon of long COVID, a condition characterized by persistent symptoms following the resolution of the acute phase of infection. ...This review aims to synt …
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has introduced the medical community to the phenomenon of long COVID, a …
Intersection of Coronavirus Disease 2019 and Alcohol-associated Liver Disease: A Review of Emerging Trends and Implications.
Aby ES, Vogel AS, Winters AC. Aby ES, et al. Clin Ther. 2023 Dec;45(12):1164-1170. doi: 10.1016/j.clinthera.2023.08.019. Epub 2023 Sep 26. Clin Ther. 2023. PMID: 37758533 Review.
PURPOSE: This review will provide an overview of alcohol use and alcohol associated liver disease (ALD) prior to the coronavirus disease 2019 (COVID-19) pandemic and the impact of the pandemic on alcohol use and ALD. ...The COVID-19 …
PURPOSE: This review will provide an overview of alcohol use and alcohol associated liver disease (ALD) prior to the coronavirus d …
A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2.
Yin Q, Luo W, Mallajosyula V, Bo Y, Guo J, Xie J, Sun M, Verma R, Li C, Constantz CM, Wagar LE, Li J, Sola E, Gupta N, Wang C, Kask O, Chen X, Yuan X, Wu NC, Rao J, Chien YH, Cheng J, Pulendran B, Davis MM. Yin Q, et al. Nat Mater. 2023 Mar;22(3):380-390. doi: 10.1038/s41563-022-01464-2. Epub 2023 Jan 30. Nat Mater. 2023. PMID: 36717665 Free PMC article.
This strategy also enhances the antibody response to a SARS-CoV-2 subunit vaccine against multiple viral variants that have emerged. Moreover, this TLR7-NP augments antigen-specific responses in human tonsil organoids. Overall, we describe a nanoparticle adjuvant to improv …
This strategy also enhances the antibody response to a SARS-CoV-2 subunit vaccine against multiple viral variants that have emerged. …
The aging of the immune system and its implications for transplantation.
McGovern KE, Sonar SA, Watanabe M, Coplen CP, Bradshaw CM, Nikolich JŽ. McGovern KE, et al. Geroscience. 2023 Jun;45(3):1383-1400. doi: 10.1007/s11357-022-00720-2. Epub 2023 Jan 10. Geroscience. 2023. PMID: 36626019 Free PMC article. Review.
This decline leads to clinical manifestations of increased susceptibility to infections, particularly those caused by emerging and reemerging microorganisms, which can reach staggering levels-infection with SARS-CoV-2 has been 270-fold more lethal to older ad …
This decline leads to clinical manifestations of increased susceptibility to infections, particularly those caused by emerging …
Mesenchymal Stromal Cells in Viral Infections: Implications for COVID-19.
Rocha JLM, de Oliveira WCF, Noronha NC, Dos Santos NCD, Covas DT, Picanço-Castro V, Swiech K, Malmegrim KCR. Rocha JLM, et al. Stem Cell Rev Rep. 2021 Feb;17(1):71-93. doi: 10.1007/s12015-020-10032-7. Stem Cell Rev Rep. 2021. PMID: 32895900 Free PMC article. Review.
We critically discuss the rationale, advantages and disadvantages of MSC-based therapies for viral infections and also specifically for COVID-19 and point out some directions in this field. Finally, we argue that MSC-based therapy may be a promising therapeut …
We critically discuss the rationale, advantages and disadvantages of MSC-based therapies for viral infections and also specifically f …
C4 article: Implications of COVID-19 in transplantation.
Contributors to the C4 article. Contributors to the C4 article. Am J Transplant. 2021 May;21(5):1801-1815. doi: 10.1111/ajt.16346. Epub 2020 Nov 6. Am J Transplant. 2021. PMID: 33040483 Free PMC article.
In this C4 article, contributors discuss various aspects of transplantation including donor and recipient screening, management of infected patients, and prevention of coronavirus disease (COVID). ...The management of COVID has evolved with remdesivir emerging …
In this C4 article, contributors discuss various aspects of transplantation including donor and recipient screening, management of …
99 results