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The host STING pathway at the interface of cancer and immunity.
Corrales L, McWhirter SM, Dubensky TW Jr, Gajewski TF. Corrales L, et al. J Clin Invest. 2016 Jul 1;126(7):2404-11. doi: 10.1172/JCI86892. Epub 2016 Jul 1. J Clin Invest. 2016. PMID: 27367184 Free PMC article. Review.
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.
Corrales L, Glickman LH, McWhirter SM, Kanne DB, Sivick KE, Katibah GE, Woo SR, Lemmens E, Banda T, Leong JJ, Metchette K, Dubensky TW Jr, Gajewski TF. Corrales L, et al. Cell Rep. 2015 May 19;11(7):1018-30. doi: 10.1016/j.celrep.2015.04.031. Epub 2015 May 7. Cell Rep. 2015. PMID: 25959818 Free PMC article.
Endogenous and pharmacologic targeting of the STING pathway in cancer immunotherapy.
Corrales L, Gajewski TF. Corrales L, et al. Cytokine. 2016 Jan;77:245-7. doi: 10.1016/j.cyto.2015.08.258. Epub 2015 Aug 24. Cytokine. 2016. PMID: 26315534 Free PMC article. No abstract available.
Innate immune mediators in cancer: between defense and resistance.
Berraondo P, Minute L, Ajona D, Corrales L, Melero I, Pio R. Berraondo P, et al. Immunol Rev. 2016 Nov;274(1):290-306. doi: 10.1111/imr.12464. Immunol Rev. 2016. PMID: 27782320 Review.
Cancer Immunotherapy Targets Based on Understanding the T Cell-Inflamed Versus Non-T Cell-Inflamed Tumor Microenvironment.
Gajewski TF, Corrales L, Williams J, Horton B, Sivan A, Spranger S. Gajewski TF, et al. Adv Exp Med Biol. 2017;1036:19-31. doi: 10.1007/978-3-319-67577-0_2. Adv Exp Med Biol. 2017. PMID: 29275462 Free PMC article. Review.
Innate immune signaling and regulation in cancer immunotherapy.
Corrales L, Matson V, Flood B, Spranger S, Gajewski TF. Corrales L, et al. Cell Res. 2017 Jan;27(1):96-108. doi: 10.1038/cr.2016.149. Epub 2016 Dec 16. Cell Res. 2017. PMID: 27981969 Free PMC article. Review.
STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia.
Curran E, Chen X, Corrales L, Kline DE, Dubensky TW Jr, Duttagupta P, Kortylewski M, Kline J. Curran E, et al. Cell Rep. 2016 Jun 14;15(11):2357-66. doi: 10.1016/j.celrep.2016.05.023. Epub 2016 Jun 2. Cell Rep. 2016. PMID: 27264175 Free PMC article.
Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA.
Corrales L, Woo SR, Williams JB, McWhirter SM, Dubensky TW Jr, Gajewski TF. Corrales L, et al. J Immunol. 2016 Apr 1;196(7):3191-8. doi: 10.4049/jimmunol.1502538. Epub 2016 Feb 29. J Immunol. 2016. PMID: 26927800 Free PMC article.
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