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Use of a mouse model of pancreatic neuroendocrine tumors to find pericyte biomarkers of resistance to anti-angiogenic therapy.
Franco M, Pàez-Ribes M, Cortez E, Casanovas O, Pietras K. Franco M, et al. Among authors: cortez e. Horm Metab Res. 2011 Nov;43(12):884-9. doi: 10.1055/s-0031-1284381. Epub 2011 Sep 29. Horm Metab Res. 2011. PMID: 21960459
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.
Roswall P, Bocci M, Bartoschek M, Li H, Kristiansen G, Jansson S, Lehn S, Sjölund J, Reid S, Larsson C, Eriksson P, Anderberg C, Cortez E, Saal LH, Orsmark-Pietras C, Cordero E, Haller BK, Häkkinen J, Burvenich IJG, Lim E, Orimo A, Höglund M, Rydén L, Moch H, Scott AM, Eriksson U, Pietras K. Roswall P, et al. Among authors: cortez e. Nat Med. 2018 May;24(4):463-473. doi: 10.1038/nm.4494. Epub 2018 Mar 12. Nat Med. 2018. PMID: 29529015 Free PMC article.
Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling.
Eleftheriou NM, Sjölund J, Bocci M, Cortez E, Lee SJ, Cunha SI, Pietras K. Eleftheriou NM, et al. Among authors: cortez e. Oncotarget. 2016 Dec 20;7(51):84314-84325. doi: 10.18632/oncotarget.12604. Oncotarget. 2016. PMID: 27741515 Free PMC article.
Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD.
Cortez E, Gladh H, Braun S, Bocci M, Cordero E, Björkström NK, Miyazaki H, Michael IP, Eriksson U, Folestad E, Pietras K. Cortez E, et al. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E864-73. doi: 10.1073/pnas.1509384113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831065 Free PMC article.
Functional subsets of mesenchymal cell types in the tumor microenvironment.
Cortez E, Roswall P, Pietras K. Cortez E, et al. Semin Cancer Biol. 2014 Apr;25:3-9. doi: 10.1016/j.semcancer.2013.12.010. Epub 2014 Jan 7. Semin Cancer Biol. 2014. PMID: 24412106 Review.
Here, we will review our current understanding of the diversity of different subsets of mesenchymal cells, i.e., cancer-associated fibroblasts and pericytes, residing within the tumor parenchyma....
Here, we will review our current understanding of the diversity of different subsets of mesenchymal cells, i.e., cancer-associated fi …
Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression.
Franco M, Roswall P, Cortez E, Hanahan D, Pietras K. Franco M, et al. Among authors: cortez e. Blood. 2011 Sep 8;118(10):2906-17. doi: 10.1182/blood-2011-01-331694. Epub 2011 Jul 21. Blood. 2011. PMID: 21778339 Free PMC article.
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.
Anderberg C, Cunha SI, Zhai Z, Cortez E, Pardali E, Johnson JR, Franco M, Páez-Ribes M, Cordiner R, Fuxe J, Johansson BR, Goumans MJ, Casanovas O, ten Dijke P, Arthur HM, Pietras K. Anderberg C, et al. Among authors: cortez e. J Exp Med. 2013 Mar 11;210(3):563-79. doi: 10.1084/jem.20120662. Epub 2013 Feb 11. J Exp Med. 2013. PMID: 23401487 Free PMC article.
Engineered high-affinity affibody molecules targeting platelet-derived growth factor receptor β in vivo.
Lindborg M, Cortez E, Höidén-Guthenberg I, Gunneriusson E, von Hage E, Syud F, Morrison M, Abrahmsén L, Herne N, Pietras K, Frejd FY. Lindborg M, et al. Among authors: cortez e. J Mol Biol. 2011 Mar 25;407(2):298-315. doi: 10.1016/j.jmb.2011.01.033. Epub 2011 Jan 28. J Mol Biol. 2011. PMID: 21277312
Image-based 3D modeling study of the influence of vessel density and blood hemoglobin concentration on tumor oxygenation and response to irradiation.
Lagerlöf JH, Kindblom J, Cortez E, Pietras K, Bernhardt P. Lagerlöf JH, et al. Among authors: cortez e. Med Phys. 2013 Feb;40(2):024101. doi: 10.1118/1.4773886. Med Phys. 2013. PMID: 23387780
Systematic review of in vitro studies evaluating tooth bleaching efficacy.
Kwon SR, Cortez E, Wang M, Jagwani M, Oyoyo U, Li Y. Kwon SR, et al. Among authors: cortez e. Am J Dent. 2020 Feb;33(1):17-24. Am J Dent. 2020. PMID: 32056410
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