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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1799 1
1823 1
1842 1
1858 1
1874 1
1875 1
1876 1
1888 1
1891 1
1893 1
1896 2
1897 1
1898 3
1899 6
1900 2
1901 4
1902 1
1903 4
1905 8
1906 1
1907 7
1908 5
1909 5
1910 16
1911 10
1912 7
1913 9
1914 20
1915 14
1916 13
1917 26
1918 13
1919 13
1920 23
1921 18
1922 16
1923 18
1924 25
1925 15
1926 21
1927 38
1928 25
1929 20
1930 36
1931 39
1932 26
1933 26
1934 28
1935 29
1936 37
1937 33
1938 31
1939 32
1940 22
1941 28
1942 23
1943 26
1944 31
1945 258
1946 503
1947 1127
1948 1535
1949 1187
1950 1431
1951 1852
1952 1824
1953 1995
1954 1921
1955 1859
1956 1724
1957 1777
1958 1867
1959 1074
1960 376
1961 523
1962 510
1963 610
1964 861
1965 1664
1966 2668
1967 2945
1968 3359
1969 3543
1970 3699
1971 3813
1972 3829
1973 3979
1974 3951
1975 5062
1976 5047
1977 5194
1978 5064
1979 5662
1980 5586
1981 6222
1982 6463
1983 7264
1984 7860
1985 7809
1986 7903
1987 8558
1988 9152
1989 10967
1990 11177
1991 11688
1992 12153
1993 12584
1994 12754
1995 13431
1996 13977
1997 14925
1998 15423
1999 15776
2000 16929
2001 17551
2002 17933
2003 19354
2004 20241
2005 21895
2006 24050
2007 25155
2008 26629
2009 28052
2010 30102
2011 32956
2012 35116
2013 36254
2014 37421
2015 38487
2016 38752
2017 39430
2018 40094
2019 39176
2020 31307
2021 8
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850,401 results
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SARS-CoV-2 detection, viral load and infectivity over the course of an infection.
Walsh KA, Jordan K, Clyne B, Rohde D, Drummond L, Byrne P, Ahern S, Carty PG, O'Brien KK, O'Murchu E, O'Neill M, Smith SM, Ryan M, Harrington P. Walsh KA, et al. J Infect. 2020 Sep;81(3):357-371. doi: 10.1016/j.jinf.2020.06.067. Epub 2020 Jun 29. J Infect. 2020. PMID: 32615199 Free PMC article.
OBJECTIVES: To summarise the evidence on the detection pattern and viral load of SARS-CoV-2 over the course of an infection (including any asymptomatic or pre-symptomatic phase), and the duration of infectivity. ...No study was found that definitively measure …
OBJECTIVES: To summarise the evidence on the detection pattern and viral load of SARS-CoV-2 over the course of an infection (i …
Milk Oligosaccharides Inhibit Human Rotavirus Infectivity in MA104 Cells.
Laucirica DR, Triantis V, Schoemaker R, Estes MK, Ramani S. Laucirica DR, et al. J Nutr. 2017 Sep;147(9):1709-1714. doi: 10.3945/jn.116.246090. Epub 2017 Jun 21. J Nutr. 2017. PMID: 28637685 Free PMC article.
Milk oligosaccharides reduce infectivity of a porcine rotavirus strain; however, the effects on human rotaviruses are less well understood.Objective: In this study, we determined the effect of specific and abundant milk oligosaccharides on the infectivity of 2
Milk oligosaccharides reduce infectivity of a porcine rotavirus strain; however, the effects on human rotaviruses are less well under …
Cost-effectiveness of IL28Β genotype-guided protease inhibitor triple therapy versus standard of care treatment in patients with hepatitis C genotypes 2 or 3 infection.
Bock JA, Fairley KJ, Smith RE, Maeng DD, Pitcavage JM, Inverso NA, Williams MS. Bock JA, et al. Public Health Genomics. 2014;17(5-6):306-19. doi: 10.1159/000365939. Epub 2014 Sep 18. Public Health Genomics. 2014. PMID: 25247313 Free PMC article.
BACKGROUND/AIMS: Triple therapy [adding protease inhibitors to standard of care (SOC)] dramatically increases treatment response in selected patients with hepatitis C virus (HCV). ...Short- and long-term costs …
BACKGROUND/AIMS: Triple therapy [adding protease inhibitors to standard of care (SOC)] dramaticall …
Canine coronavirus inactivation with physical and chemical agents.
Pratelli A. Pratelli A. Vet J. 2008 Jul;177(1):71-9. doi: 10.1016/j.tvjl.2007.03.019. Epub 2007 May 21. Vet J. 2008. PMID: 17513145 Free PMC article.
CCoV infectivity was stable at +56 degrees C for up to 30 min, but tended to decrease rapidly at +65 degrees C and +75 degrees C. Germicidal ultra-violet (UV-C) light exposure demonstrated no significant effects on virus inactivation for up to …
CCoV infectivity was stable at +56 degrees C for up to 30 min, but tended to decrease rapidly at +65 degrees C and +75 …
Competitive advantage of a dengue 4 virus when co-infecting the mosquito Aedes aegypti with a dengue 1 virus.
Vazeille M, Gaborit P, Mousson L, Girod R, Failloux AB. Vazeille M, et al. BMC Infect Dis. 2016 Jul 8;16:318. doi: 10.1186/s12879-016-1666-0. BMC Infect Dis. 2016. PMID: 27390932 Free PMC article.
South American countries have seen the reemergence of DENV since the 1970's associated with the progressive re-infestation by the mosquito vector, Aedes aegypti. ...We performed oral artificial infections of F1 populations in BSL-3 conditions and analyzed …
South American countries have seen the reemergence of DENV since the 1970's associated with the progressive re-infestation by the mos …
Virulence of beta-hemolytic streptococci in infective endocarditis.
Ruch Y, Hansmann Y, Riegel P, Lefebvre N, Mazzucotelli JP, Douiri N, Martin A, Argemi X. Ruch Y, et al. Infection. 2020 Feb;48(1):91-97. doi: 10.1007/s15010-019-01358-7. Epub 2019 Sep 13. Infection. 2020. PMID: 31520396
The rates of septic shock and cerebral emboli were also higher in the BHS group than in the ANHS group [n = 7 (29.2%) vs. n = 3 (3.1%), p < 0.001; n = 7 (29.2%) vs. n = 12 (12.5%); p = 0.05, respectively]. ...The virulence of BHS may be similar to t …
The rates of septic shock and cerebral emboli were also higher in the BHS group than in the ANHS group [n = 7 (29.2%) vs. n = 3
SARS-CoV-2: The viral shedding vs infectivity dilemma.
Widders A, Broom A, Broom J. Widders A, et al. Infect Dis Health. 2020 Aug;25(3):210-215. doi: 10.1016/j.idh.2020.05.002. Epub 2020 May 20. Infect Dis Health. 2020. PMID: 32473952 Free PMC article.
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people worldwide. There are multiple reports of prolonged viral shedding in people infected with SARS-CoV-2 but the presence of vira …
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people …
Staphylococcus aureus Impacts Pseudomonas aeruginosa Chronic Respiratory Disease in Murine Models.
Cigana C, Bianconi I, Baldan R, De Simone M, Riva C, Sipione B, Rossi G, Cirillo DM, Bragonzi A. Cigana C, et al. J Infect Dis. 2018 Mar 5;217(6):933-942. doi: 10.1093/infdis/jix621. J Infect Dis. 2018. PMID: 29216403
First, mice were infected with S. aureus, embedded in agar beads; this was followed by P. aeruginosa infection and analysis of bacterial load, leukocyte infiltration, and lung tissue damage. RESULTS: We reveal that (1) S. aureus promotes severe …
First, mice were infected with S. aureus, embedded in agar beads; this was followed by P. aeruginosa infection and a
Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models.
Kotani O, Naeem A, Suzuki T, Iwata-Yoshikawa N, Sato Y, Nakajima N, Hosomi T, Tsukagoshi H, Kozawa K, Hasegawa H, Taguchi F, Shimizu H, Nagata N. Kotani O, et al. PLoS One. 2016 Feb 1;11(2):e0148184. doi: 10.1371/journal.pone.0148184. eCollection 2016. PLoS One. 2016. PMID: 26828718 Free PMC article.
Both clinical isolates were infective, exhibited neurotropism, and were mildly neurovirulent in neonatal ddY mice. Both strains pathologically infected neural progenitor cells and glial cells, but not large neurons, with the UR strain also infecting epithelia …
Both clinical isolates were infective, exhibited neurotropism, and were mildly neurovirulent in neonatal ddY mice. Both strains patho …
Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice.
Vanwolleghem T, Libbrecht L, Hansen BE, Desombere I, Roskams T, Meuleman P, Leroux-Roels G. Vanwolleghem T, et al. J Hepatol. 2010 Sep;53(3):468-76. doi: 10.1016/j.jhep.2010.03.024. Epub 2010 May 31. J Hepatol. 2010. PMID: 20591528
BACKGROUND & AIMS: The human liver-uPA(+/+)-SCID mouse is currently the best small animal model available for viral hepatitis infection studies. ...HCV infection rate varied substantially, although every donor cell type yielded infectable animals. …
BACKGROUND & AIMS: The human liver-uPA(+/+)-SCID mouse is currently the best small animal model available for viral hepatitis
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