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HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.
Zirkel A, Nikolic M, Sofiadis K, Mallm JP, Brackley CA, Gothe H, Drechsel O, Becker C, Altmüller J, Josipovic N, Georgomanolis T, Brant L, Franzen J, Koker M, Gusmao EG, Costa IG, Ullrich RT, Wagner W, Roukos V, Nürnberg P, Marenduzzo D, Rippe K, Papantonis A. Zirkel A, et al. Among authors: costa ig. Mol Cell. 2018 May 17;70(4):730-744.e6. doi: 10.1016/j.molcel.2018.03.030. Epub 2018 Apr 26. Mol Cell. 2018. PMID: 29706538 Free article.
Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites.
Hänzelmann S, Beier F, Gusmao EG, Koch CM, Hummel S, Charapitsa I, Joussen S, Benes V, Brümmendorf TH, Reid G, Costa IG, Wagner W. Hänzelmann S, et al. Among authors: costa ig. Clin Epigenetics. 2015 Mar 4;7(1):19. doi: 10.1186/s13148-015-0057-5. eCollection 2015. Clin Epigenetics. 2015. PMID: 25763115 Free PMC article.
Epigenetic program and transcription factor circuitry of dendritic cell development.
Lin Q, Chauvistré H, Costa IG, Gusmao EG, Mitzka S, Hänzelmann S, Baying B, Klisch T, Moriggl R, Hennuy B, Smeets H, Hoffmann K, Benes V, Seré K, Zenke M. Lin Q, et al. Among authors: costa ig. Nucleic Acids Res. 2015 Nov 16;43(20):9680-93. doi: 10.1093/nar/gkv1056. Epub 2015 Oct 17. Nucleic Acids Res. 2015. PMID: 26476451 Free PMC article.
Epigenetic Classification of Human Mesenchymal Stromal Cells.
de Almeida DC, Ferreira MR, Franzen J, Weidner CI, Frobel J, Zenke M, Costa IG, Wagner W. de Almeida DC, et al. Among authors: costa ig. Stem Cell Reports. 2016 Feb 9;6(2):168-75. doi: 10.1016/j.stemcr.2016.01.003. Stem Cell Reports. 2016. PMID: 26862701 Free PMC article.
Binding of nuclear factor κB to noncanonical consensus sites reveals its multimodal role during the early inflammatory response.
Kolovos P, Georgomanolis T, Koeferle A, Larkin JD, Brant L, Nikolicć M, Gusmao EG, Zirkel A, Knoch TA, van Ijcken WF, Cook PR, Costa IG, Grosveld FG, Papantonis A. Kolovos P, et al. Among authors: costa ig. Genome Res. 2016 Nov;26(11):1478-1489. doi: 10.1101/gr.210005.116. Epub 2016 Sep 15. Genome Res. 2016. PMID: 27633323 Free PMC article.
145 results