Costa M - Search Results

1

Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis.

Tian H, Biehs B, Chiu C, Siebel CW, Wu Y, Costa M, de Sauvage FJ, Klein OD. Tian H, et al. Among authors: costa m. Cell Rep. 2015 Apr 7;11(1):33-42. doi: 10.1016/j.celrep.2015.03.007. Epub 2015 Mar 26. Cell Rep. 2015. PMID: 25818302 Free PMC article.

2

Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies.

Gong Y, Bourhis E, Chiu C, Stawicki S, DeAlmeida VI, Liu BY, Phamluong K, Cao TC, Carano RA, Ernst JA, Solloway M, Rubinfeld B, Hannoush RN, Wu Y, Polakis P, Costa M. Gong Y, et al. Among authors: costa m. PLoS One. 2010 Sep 13;5(9):e12682. doi: 10.1371/journal.pone.0012682. PLoS One. 2010. PMID: 20856934 Free PMC article.

3

Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6.

Bourhis E, Wang W, Tam C, Hwang J, Zhang Y, Spittler D, Huang OW, Gong Y, Estevez A, Zilberleyb I, Rouge L, Chiu C, Wu Y, Costa M, Hannoush RN, Franke Y, Cochran AG. Bourhis E, et al. Among authors: costa m. Structure. 2011 Oct 12;19(10):1433-42. doi: 10.1016/j.str.2011.07.005. Epub 2011 Sep 22. Structure. 2011. PMID: 21944579 Free article.

4

TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling.

Junge HJ, Yang S, Burton JB, Paes K, Shu X, French DM, Costa M, Rice DS, Ye W. Junge HJ, et al. Among authors: costa m. Cell. 2009 Oct 16;139(2):299-311. doi: 10.1016/j.cell.2009.07.048. Cell. 2009. PMID: 19837033 Free article.

5

Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1.

Zhong Y, Katavolos P, Nguyen T, Lau T, Boggs J, Sambrone A, Kan D, Merchant M, Harstad E, Diaz D, Costa M, Schutten M. Zhong Y, et al. Among authors: costa m. Toxicol Pathol. 2016 Feb;44(2):267-78. doi: 10.1177/0192623315621192. Epub 2015 Dec 20. Toxicol Pathol. 2016. PMID: 26692561

6

CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing.

Callow MG, Watanabe C, Wickliffe KE, Bainer R, Kummerfield S, Weng J, Cuellar T, Janakiraman V, Chen H, Chih B, Liang Y, Haley B, Newton K, Costa MR. Callow MG, et al. Cell Death Dis. 2018 Feb 15;9(3):261. doi: 10.1038/s41419-018-0301-y. Cell Death Dis. 2018. PMID: 29449584 Free PMC article.

7

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M. Lau T, et al. Among authors: costa m. Cancer Res. 2013 May 15;73(10):3132-44. doi: 10.1158/0008-5472.CAN-12-4562. Epub 2013 Mar 28. Cancer Res. 2013. PMID: 23539443

8

Inhibition of Wnt signaling by Dishevelled PDZ peptides.

Zhang Y, Appleton BA, Wiesmann C, Lau T, Costa M, Hannoush RN, Sidhu SS. Zhang Y, et al. Among authors: costa m. Nat Chem Biol. 2009 Apr;5(4):217-9. doi: 10.1038/nchembio.152. Epub 2009 Mar 1. Nat Chem Biol. 2009. PMID: 19252499

9

Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.

Bourhis E, Tam C, Franke Y, Bazan JF, Ernst J, Hwang J, Costa M, Cochran AG, Hannoush RN. Bourhis E, et al. Among authors: costa m. J Biol Chem. 2010 Mar 19;285(12):9172-9. doi: 10.1074/jbc.M109.092130. Epub 2010 Jan 21. J Biol Chem. 2010. PMID: 20093360 Free PMC article.

10

Bidirectional effect of Wnt signaling antagonist DKK1 on the modulation of anthrax toxin uptake.

Qian L, Cai C, Yuan P, Jeong SY, Yang X, Dealmeida V, Ernst J, Costa M, Cohen SN, Wei W. Qian L, et al. Among authors: costa m. Sci China Life Sci. 2014 May;57(5):469-81. doi: 10.1007/s11427-014-4646-x. Epub 2014 Mar 26. Sci China Life Sci. 2014. PMID: 24671437

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