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GDNF signalling through the Ret receptor tyrosine kinase.
Durbec P, Marcos-Gutierrez CV, Kilkenny C, Grigoriou M, Wartiowaara K, Suvanto P, Smith D, Ponder B, Costantini F, Saarma M, et al. Durbec P, et al. Among authors: costantini f. Nature. 1996 Jun 27;381(6585):789-93. doi: 10.1038/381789a0. Nature. 1996. PMID: 8657282
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.
Lu BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, D'Agati V, Costantini F. Lu BC, et al. Among authors: costantini f. Nat Genet. 2009 Dec;41(12):1295-302. doi: 10.1038/ng.476. Epub 2009 Nov 8. Nat Genet. 2009. PMID: 19898483 Free PMC article.
Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra.
Mijatovic J, Airavaara M, Planken A, Auvinen P, Raasmaja A, Piepponen TP, Costantini F, Ahtee L, Saarma M. Mijatovic J, et al. Among authors: costantini f. J Neurosci. 2007 May 2;27(18):4799-809. doi: 10.1523/JNEUROSCI.5647-06.2007. J Neurosci. 2007. PMID: 17475787 Free PMC article.
Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction.
Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD. Basson MA, et al. Dev Cell. 2005 Feb;8(2):229-39. doi: 10.1016/j.devcel.2004.12.004. Dev Cell. 2005. PMID: 15691764 Free article.
284 results