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Page 1
Feminizing hormone therapy in a Canadian cohort of transgender women with and without HIV.
Armstrong I, Lacombe-Duncan A, Shokoohi M, Persad Y, Tseng A, Fung R, Underhill A, Côté P, Machouf N, Saucier A, Varriano B, Brundage M, Jones R, Weisdorf T, Goodhew J, MacLeod J, Loutfy M. Armstrong I, et al. Among authors: cote p. Antivir Ther. 2023 Jun;28(3):13596535231182505. doi: 10.1177/13596535231182505. Antivir Ther. 2023. PMID: 37289725 Free article.
BACKGROUND: Potential bidirectional drug-drug interactions between feminizing hormone therapy (FHT) and antiretroviral therapy (ART) are of concern for trans women with HIV and their healthcare providers. This study aimed to characterize patterns of FHT and ART among trans …
BACKGROUND: Potential bidirectional drug-drug interactions between feminizing hormone therapy (FHT) and antiretroviral therapy (ART) are of …
Influence of NKG2C Genotypes on HIV Susceptibility and Viral Load Set Point.
Alsulami K, Bolastig N, Dupuy FP, Mabanga T, Gilbert L, Kiani Z, Routy JP, Bruneau J, Thomas R, Tremblay C, Tsoukas CM, Szabo J, Côté P, Trottier B, LeBlanc R, Rouleau D, Bernard NF; investigators in the Montreal Primary HIV Infection cohort. Alsulami K, et al. Among authors: cote p. J Virol. 2021 Jul 26;95(16):e0041721. doi: 10.1128/JVI.00417-21. Epub 2021 Jul 26. J Virol. 2021. PMID: 34076484 Free PMC article.
Previous reports found that carriage of the deleted NKG2C(-) variant was more frequent in people living with HIV (PLWH) than in HIV(-) controls unexposed to HIV. The frequency of NKG2C(+) NK cells positively correlated with HIV viral load (VL) in some …
Previous reports found that carriage of the deleted NKG2C(-) variant was more frequent in people living with HIV (PLWH) than in HI …
Evolution of Antibodies to Native Trimeric Envelope and Their Fc-Dependent Functions in Untreated and Treated Primary HIV Infection.
Nagel L, Kant S, Leeks C, Routy JP, Tremblay C, Thomas R, Szabo J, Côté P, Trottier B, LeBlanc R, Rouleau D, Dupuy FP, Bernard NF; investigators in Montreal Primary HIV Infection cohort. Nagel L, et al. Among authors: cote p. J Virol. 2021 Nov 23;95(24):e0162521. doi: 10.1128/JVI.01625-21. Epub 2021 Sep 29. J Virol. 2021. PMID: 34586863 Free PMC article.
IMPORTANCE Closed-conformation envelope is expressed on the surface of HIV-infected cells. Antibodies targeting this conformation and that support FcDFs have the potential to control HIV. ...This information may be useful in making decisions on the timing of ART ini …
IMPORTANCE Closed-conformation envelope is expressed on the surface of HIV-infected cells. Antibodies targeting this conformation and …
Circulating (1→3)-β-D-glucan Is Associated With Immune Activation During Human Immunodeficiency Virus Infection.
Mehraj V, Ramendra R, Isnard S, Dupuy FP, Ponte R, Chen J, Kema I, Jenabian MA, Costinuik CT, Lebouché B, Thomas R, Coté P, Leblanc R, Baril JG, Durand M, Chartrand-Lefebvre C, Tremblay C, Ancuta P, Bernard NF, Sheppard DC, Routy JP; Montreal Primary HIV Infection Study and Canadian HIV and Aging Cohort Study Groups. Mehraj V, et al. Among authors: cote p. Clin Infect Dis. 2020 Jan 2;70(2):232-241. doi: 10.1093/cid/ciz212. Clin Infect Dis. 2020. PMID: 30877304 Free PMC article.
BACKGROUND: Microbial translocation from the gut to systemic circulation contributes to immune activation during human immunodeficiency virus (HIV) infection and is usually assessed by measuring plasma levels of bacterial lipopolysaccharide (LPS). Fungal colonization in th …
BACKGROUND: Microbial translocation from the gut to systemic circulation contributes to immune activation during human immunodeficiency viru …
HIV prevalence among a retrospective clinical cohort of transgender women in Canada: Results of the Montreal-Toronto Trans study, collected 2018-2019.
Lacombe-Duncan A, Persad Y, Shokoohi M, Underhill A, Cote P, Wheatley M, Gupta M, Kyne LT, Besharati AA, Chan LL, Hranilovic S, Nguyen Q, Loutfy M. Lacombe-Duncan A, et al. Among authors: cote p. Int J STD AIDS. 2023 Dec;34(14):1062-1071. doi: 10.1177/09564624231185818. Epub 2023 Aug 16. Int J STD AIDS. 2023. PMID: 37586721
METHODS: Retrospective chart data of trans women aged 16+ were collected from six family medicine and/or HIV clinics in Montreal and Toronto, Canada, 2018-2019. Multinomial logistic regression was used to analyze factors associated with documented HIV positive or mi …
METHODS: Retrospective chart data of trans women aged 16+ were collected from six family medicine and/or HIV clinics in Montreal and …
Short report: Characterizing HIV care among a clinical sample of transgender women living with HIV.
Lacombe-Duncan A, Shokoohi M, Persad Y, Underhill A, Machouf N, Côté P, Wheatley M, Gupta M, Kyne LT, Besharati AA, Fung R, Chan LYL, Arbess G, Bourns A, Nguyen Q, Loutfy M. Lacombe-Duncan A, et al. Among authors: cote p. HIV Med. 2022 Apr;23(4):324-330. doi: 10.1111/hiv.13261. Epub 2022 Feb 22. HIV Med. 2022. PMID: 35193172 Free article.
INTRODUCTION: This study aimed to characterize and identify factors associated with HIV care among transgender (trans) women living with HIV (TWLWH) in two urban centres in Canada. ...Although not statistically significant, 96.2% of those currently reporting feminiz …
INTRODUCTION: This study aimed to characterize and identify factors associated with HIV care among transgender (trans) women living w …
CXCL13 as a Biomarker of Immune Activation During Early and Chronic HIV Infection.
Mehraj V, Ramendra R, Isnard S, Dupuy FP, Lebouché B, Costiniuk C, Thomas R, Szabo J, Baril JG, Trottier B, Coté P, LeBlanc R, Durand M, Chartrand-Lefebvre C, Kema I, Zhang Y, Finkelman M, Tremblay C, Routy JP. Mehraj V, et al. Among authors: cote p. Front Immunol. 2019 Feb 21;10:289. doi: 10.3389/fimmu.2019.00289. eCollection 2019. Front Immunol. 2019. PMID: 30846990 Free PMC article.
Methods: Study samples were collected in 114 people living with HIV (PLWH) who were in early (EHI) or chronic (CHI) HIV infection and 35 elite controllers (EC) compared to 17 uninfected controls (UC). ...Conclusion: Plasma CXCL13 levels increased with HIV dis …
Methods: Study samples were collected in 114 people living with HIV (PLWH) who were in early (EHI) or chronic (CHI) HIV infect …
Quantifying Anti-HIV Envelope-Specific Antibodies in Plasma from HIV Infected Individuals.
Kant S, Zhang N, Routy JP, Tremblay C, Thomas R, Szabo J, Côté P, Trottier B, LeBlanc R, Rouleau D, Harris M, Dupuy FP, Bernard NF. Kant S, et al. Among authors: cote p. Viruses. 2019 May 28;11(6):487. doi: 10.3390/v11060487. Viruses. 2019. PMID: 31141927 Free PMC article.
Quantifying HIV Envelope (Env)-specific antibodies in HIV(+) plasma is useful for interpreting antibody dependent cellular cytotoxicity assay results. HIV Env, the only viral protein expressed on the surface of infected cells, has a native trimeric closed con …
Quantifying HIV Envelope (Env)-specific antibodies in HIV(+) plasma is useful for interpreting antibody dependent cellular cyt …
HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness.
Jackson E, Zhang CX, Kiani Z, Lisovsky I, Tallon B, Del Corpo A, Gilbert L, Bruneau J, Thomas R, Côté P, Trottier B, LeBlanc R, Rouleau D, Tremblay C, Tsoukas CM, Routy JP, Ni X, Mabanga T, Bernard NF; Montreal Primary Infection Study Group. Jackson E, et al. Among authors: cote p. PLoS One. 2017 Sep 22;12(9):e0185160. doi: 10.1371/journal.pone.0185160. eCollection 2017. PLoS One. 2017. PMID: 28938026 Free PMC article.
Previously, we showed that Killer Immunoglobulin-like Receptor (KIR)3DS1 homozygotes (hmz) are more frequent in HIV exposed seronegative (HESN) than in recently HIV infected (HIV+) individuals. KIR3DS1 encodes an activating Natural Killer (NK) cell receptor ( …
Previously, we showed that Killer Immunoglobulin-like Receptor (KIR)3DS1 homozygotes (hmz) are more frequent in HIV exposed seronegat …
Polyfunctional Fc Dependent Activity of Antibodies to Native Trimeric Envelope in HIV Elite Controllers.
Kant S, Zhang N, Barbé A, Routy JP, Tremblay C, Thomas R, Szabo J, Côté P, Trottier B, LeBlanc R, Rouleau D, Harris M, Dupuy FP, Bernard NF. Kant S, et al. Among authors: cote p. Front Immunol. 2020 Sep 30;11:583820. doi: 10.3389/fimmu.2020.583820. eCollection 2020. Front Immunol. 2020. PMID: 33101312 Free PMC article.
Antibody dependent (AD) functions such as AD cellular cytotoxicity (ADCC) were associated with lower viral load (VL) in untreated HIV progressors and protection from HIV infection in the modestly protective RV144 HIV vaccine trial. ...Here, we examined ADCC, …
Antibody dependent (AD) functions such as AD cellular cytotoxicity (ADCC) were associated with lower viral load (VL) in untreated HIV …
36 results