Coughtrie MW - Search Results

1

Purification and properties of rat kidney UDP-glucuronosyltransferase.

Coughtrie MW, Burchell B, Bend JR. Coughtrie MW, et al. Biochem Pharmacol. 1987 Jan 15;36(2):245-51. doi: 10.1016/0006-2952(87)90696-4. Biochem Pharmacol. 1987. PMID: 3101703

2

Comparison of 2-aminophenol and 4-nitrophenol as in vitro probe substrates for the major human hepatic sulfotransferase, SULT1A1, demonstrates improved selectivity with 2-aminophenol.

Riches Z, Bloomer JC, Coughtrie MW. Riches Z, et al. Among authors: coughtrie mw. Biochem Pharmacol. 2007 Jul 15;74(2):352-8. doi: 10.1016/j.bcp.2007.04.006. Epub 2007 Apr 7. Biochem Pharmacol. 2007. PMID: 17506995

3

Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family.

Kobayashi T, Sleeman JE, Coughtrie MW, Burchell B. Kobayashi T, et al. Among authors: coughtrie mw. Biochem J. 2006 Dec 1;400(2):281-9. doi: 10.1042/BJ20060429. Biochem J. 2006. PMID: 16965264 Free PMC article.

4

Evidence for multiple glucuronide transporters in rat liver microsomes.

Csala M, Staines AG, Bánhegyi G, Mandl J, Coughtrie MW, Burchell B. Csala M, et al. Among authors: coughtrie mw. Biochem Pharmacol. 2004 Oct 1;68(7):1353-62. doi: 10.1016/j.bcp.2004.05.055. Biochem Pharmacol. 2004. PMID: 15345325

5

Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.

Staines AG, Sindelar P, Coughtrie MW, Burchell B. Staines AG, et al. Among authors: coughtrie mw. Biochem J. 2004 Dec 15;384(Pt 3):637-45. doi: 10.1042/BJ20040997. Biochem J. 2004. PMID: 15320866 Free PMC article.

6

Phenol sulfotransferase 1A1 activity in human liver: kinetic properties, interindividual variation and re-evaluation of the suitability of 4-nitrophenol as a probe substrate.

Tabrett CA, Coughtrie MW. Tabrett CA, et al. Among authors: coughtrie mw. Biochem Pharmacol. 2003 Dec 1;66(11):2089-97. doi: 10.1016/s0006-2952(03)00582-3. Biochem Pharmacol. 2003. PMID: 14609733

7

Development of human liver UDP-glucuronosyltransferases.

Burchell B, Coughtrie M, Jackson M, Harding D, Fournel-Gigleux S, Leakey J, Hume R. Burchell B, et al. Dev Pharmacol Ther. 1989;13(2-4):70-7. doi: 10.1159/000457587. Dev Pharmacol Ther. 1989. PMID: 2515047

8

Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme.

Coughtrie MW, Burchell B, Shepherd IM, Bend JR. Coughtrie MW, et al. Mol Pharmacol. 1987 Jun;31(6):585-91. Mol Pharmacol. 1987. PMID: 3110589

9

The molecular basis of the inherited deficiency of androsterone UDP-glucuronyltransferase in Wistar rats.

Corser RB, Coughtrie MW, Jackson MR, Burchell B. Corser RB, et al. Among authors: coughtrie mw. FEBS Lett. 1987 Mar 23;213(2):448-52. doi: 10.1016/0014-5793(87)81540-5. FEBS Lett. 1987. PMID: 2881811 Free article.

10

The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes.

Coughtrie MW, Burchell B, Leakey JE, Hume R. Coughtrie MW, et al. Mol Pharmacol. 1988 Dec;34(6):729-35. Mol Pharmacol. 1988. PMID: 3143908

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