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The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models.
Garcia PL, Miller AL, Kreitzburg KM, Council LN, Gamblin TL, Christein JD, Heslin MJ, Arnoletti JP, Richardson JH, Chen D, Hanna CA, Cramer SL, Yang ES, Qi J, Bradner JE, Yoon KJ. Garcia PL, et al. Among authors: council ln. Oncogene. 2016 Feb 18;35(7):833-45. doi: 10.1038/onc.2015.126. Epub 2015 May 11. Oncogene. 2016. PMID: 25961927 Free PMC article.
JQ1 Induces DNA Damage and Apoptosis, and Inhibits Tumor Growth in a Patient-Derived Xenograft Model of Cholangiocarcinoma.
Garcia PL, Miller AL, Gamblin TL, Council LN, Christein JD, Arnoletti JP, Heslin MJ, Reddy S, Richardson JH, Cui X, van Waardenburg RCAM, Bradner JE, Yang ES, Yoon KJ. Garcia PL, et al. Among authors: council ln. Mol Cancer Ther. 2018 Jan;17(1):107-118. doi: 10.1158/1535-7163.MCT-16-0922. Epub 2017 Nov 15. Mol Cancer Ther. 2018. PMID: 29142067 Free PMC article.
Pediatric Anaplastic Embryonal Rhabdomyosarcoma: Targeted Therapy Guided by Genetic Analysis and a Patient-Derived Xenograft Study.
Cramer SL, Miller AL, Pressey JG, Gamblin TL, Beierle EA, Kulbersh BD, Garcia PL, Council LN, Radhakrishnan R, Hendrix SV, Kelly DR, Watts RG, Yoon KJ. Cramer SL, et al. Among authors: council ln. Front Oncol. 2018 Jan 11;7:327. doi: 10.3389/fonc.2017.00327. eCollection 2017. Front Oncol. 2018. PMID: 29376028 Free PMC article.
23 results