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Circadian variations in the renal toxicity of gentamicin in rats.
Pariat C, Courtois P, Cambar J, Piriou A, Bouquet S. Pariat C, et al. Toxicol Lett. 1988 Feb;40(2):175-82. doi: 10.1016/0378-4274(88)90159-2. Toxicol Lett. 1988. PMID: 2893472
Increased excretion of gamma-glutamyl transferase, alanine aminopeptidase and N-acetyl-beta-D-glucosaminidase, used clinically as markers for tubule toxicity of aminoglycosides, was maximal when gentamicin was administered to rats at 2 p.m. and was minimal when injected at …
Increased excretion of gamma-glutamyl transferase, alanine aminopeptidase and N-acetyl-beta-D-glucosaminidase, used clinically as markers fo …
Nephrotoxicity of gentamicin and vancomycin given alone and in combination as determined by enzymuria and cortical antibiotic levels in rats.
Fauconneau B, Favrelière S, Pariat C, Génévrier A, Courtois P, Piriou A, Bouquet S. Fauconneau B, et al. Ren Fail. 1997 Jan;19(1):15-22. doi: 10.3109/08860229709026256. Ren Fail. 1997. PMID: 9044448

AAP, GGT, and NAG excretions were significantly increased after G and G + V injections (p < 0.001), whereas only AAP and GGT were statistically higher in rats receiving V (p < 0.05). NAG elimination (mean +/- SD) was higher in G + V (16.0 +/- 0.2 IU/mmol creat

AAP, GGT, and NAG excretions were significantly increased after G and G + V injections (p < 0.001), whereas only AAP and GGT were

A comparative study of enzymuria, in the rat, of the drug combinations amikacin/vancomycin and amikacin/teicoplanin.
Fauconneau B, Pariat C, Bouquet S, Piriou A, Ingrand P, Courtois P. Fauconneau B, et al. Ren Fail. 1993;15(4):469-73. doi: 10.3109/08860229309054961. Ren Fail. 1993. PMID: 8105516
The first group received 50 mg.kg-1 of amikacin (i.m. route) and 100 mg.kg-1 of vancomycin (i.p. route). The second group received 50 mg.kg-1 of amikacin (i.m. route) and 40 mg.kg-1 of teicoplanin (i.p. route). ...There were no significant modifications in the urina …
The first group received 50 mg.kg-1 of amikacin (i.m. route) and 100 mg.kg-1 of vancomycin (i.p. route). The second group received 50 …
[Demonstration of seasonal variations of circadian rhythm in gentamicin-induced chrono-nephrotoxicity in rats].
Pariat C, Courtois P, Cambar J, Bouquet S, Piriou A. Pariat C, et al. Pathol Biol (Paris). 1988 May;36(5):517-20. Pathol Biol (Paris). 1988. PMID: 2900489 French.
These excretions peak out at 8 p.m. and reach a through at 8 a.m. for the experimentation in january-february. In contrast, for the experimentation in June-July, we evidence gamma-glutamyl-transferase and alanine aminopeptidase excretion increased at 2 p.m. and decr …
These excretions peak out at 8 p.m. and reach a through at 8 a.m. for the experimentation in january-february. In contrast, for the e …
Seasonal effects on the daily variations of gentamicin-induced nephrotoxicity.
Pariat C, Ingrand P, Cambar J, de Lemos E, Piriou A, Courtois P. Pariat C, et al. Arch Toxicol. 1990;64(3):205-9. doi: 10.1007/BF02010726. Arch Toxicol. 1990. PMID: 1973611
Chrononephrotoxicity in rat of a vancomycin and gentamicin combination.
Fauconneau B, De Lemos E, Pariat C, Bouquet S, Courtois P, Piriou A. Fauconneau B, et al. Pharmacol Toxicol. 1992 Jul;71(1):31-6. doi: 10.1111/j.1600-0773.1992.tb00516.x. Pharmacol Toxicol. 1992. PMID: 1355906
., 2 p.m., 8 p.m., and 2 a.m. and urine excretion values for AAP, gamma GT and NAG were determined 24 hr later. The results show that the nephrotoxicity of gentamicin + vancomycin is greater than that observed with gentamicin, which again is greater than that observ …
., 2 p.m., 8 p.m., and 2 a.m. and urine excretion values for AAP, gamma GT and NAG were determined 24 hr later. The results sh …
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