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The vanG glycopeptide resistance operon from Enterococcus faecalis revisited.
Depardieu F, Bonora MG, Reynolds PE, Courvalin P. Depardieu F, et al. Among authors: courvalin p. Mol Microbiol. 2003 Nov;50(3):931-48. doi: 10.1046/j.1365-2958.2003.03737.x. Mol Microbiol. 2003. PMID: 14617152
The 5' end of the gene cluster contained three genes vanU(G), vanR(G) and vanS(G) encoding a putative regulatory system, which were co-transcribed constitutively from the PY(G) promoter, whereas transcription of vanY(G),W(G),G,XY(G),T(G) was inducible and initiated from the P
The 5' end of the gene cluster contained three genes vanU(G), vanR(G) and vanS(G) encoding a putative regulatory system, which were co-trans …
Why is antibiotic resistance a deadly emerging disease?
Courvalin P. Courvalin P. Clin Microbiol Infect. 2016 May;22(5):405-7. doi: 10.1016/j.cmi.2016.01.012. Epub 2016 Jan 22. Clin Microbiol Infect. 2016. PMID: 26806259 Review.
Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases.
Meziane-Cherif D, Stogios PJ, Evdokimova E, Egorova O, Savchenko A, Courvalin P. Meziane-Cherif D, et al. Among authors: courvalin p. mBio. 2015 Aug 11;6(4):e00806. doi: 10.1128/mBio.00806-15. mBio. 2015. PMID: 26265719 Free PMC article.
Structural and functional plasticity of antibiotic resistance nucleotidylyltransferases revealed by molecular characterization of lincosamide nucleotidylyltransferases lnu(A) and lnu(D).
Stogios PJ, Evdokimova E, Morar M, Koteva K, Wright GD, Courvalin P, Savchenko A. Stogios PJ, et al. Among authors: courvalin p. J Mol Biol. 2015 Jun 19;427(12):2229-43. doi: 10.1016/j.jmb.2015.04.008. Epub 2015 Apr 18. J Mol Biol. 2015. PMID: 25900373 Free PMC article.
Structural and functional characterization of VanG D-Ala:D-Ser ligase associated with vancomycin resistance in Enterococcus faecalis.
Meziane-Cherif D, Saul FA, Haouz A, Courvalin P. Meziane-Cherif D, et al. Among authors: courvalin p. J Biol Chem. 2012 Nov 2;287(45):37583-92. doi: 10.1074/jbc.M112.405522. Epub 2012 Sep 11. J Biol Chem. 2012. PMID: 22969085 Free PMC article.
Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM.
Galimand M, Schmitt E, Panvert M, Desmolaize B, Douthwaite S, Mechulam Y, Courvalin P. Galimand M, et al. Among authors: courvalin p. RNA. 2011 Feb;17(2):251-62. doi: 10.1261/rna.2233511. Epub 2010 Dec 15. RNA. 2011. PMID: 21159796 Free PMC article.
Crystallization and preliminary X-ray analysis of a D-Ala:D-Ser ligase associated with VanG-type vancomycin resistance.
Weber P, Meziane-Cherif D, Haouz A, Saul FA, Courvalin P. Weber P, et al. Among authors: courvalin p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt 10):1024-6. doi: 10.1107/S1744309109033831. Epub 2009 Sep 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19851013 Free PMC article.
A vanG-type locus in Clostridium argentinense.
Berthet N, Périchon B, Mazuet C, Chapetón-Montes D, Bouchier C, Bouvet P, Legeay C, Popoff MR, Courvalin P. Berthet N, et al. Among authors: courvalin p. J Antimicrob Chemother. 2015 Jul;70(7):1942-5. doi: 10.1093/jac/dkv073. Epub 2015 Mar 22. J Antimicrob Chemother. 2015. PMID: 25802283
RND-type efflux pumps in multidrug-resistant clinical isolates of Acinetobacter baumannii: major role for AdeABC overexpression and AdeRS mutations.
Yoon EJ, Courvalin P, Grillot-Courvalin C. Yoon EJ, et al. Among authors: courvalin p. Antimicrob Agents Chemother. 2013 Jul;57(7):2989-95. doi: 10.1128/AAC.02556-12. Epub 2013 Apr 15. Antimicrob Agents Chemother. 2013. PMID: 23587960 Free PMC article.
RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family.
Galimand M, Courvalin P, Lambert T. Galimand M, et al. Among authors: courvalin p. Antimicrob Agents Chemother. 2012 Jul;56(7):3960-2. doi: 10.1128/AAC.00660-12. Epub 2012 Apr 30. Antimicrob Agents Chemother. 2012. PMID: 22547620 Free PMC article.
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