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Key role for spinal dorsal horn microglial kinin B1 receptor in early diabetic pain neuropathy.
Talbot S, Chahmi E, Dias JP, Couture R. Talbot S, et al. J Neuroinflammation. 2010 Jun 29;7(1):36. doi: 10.1186/1742-2094-7-36. J Neuroinflammation. 2010. PMID: 20587056 Free PMC article.
Effects of intrathecal and/or systemic administration of B1R agonist (des-Arg9-BK) and antagonists (SSR240612 and R-715) were measured on neuropathic pain manifestations. ...
Effects of intrathecal and/or systemic administration of B1R agonist (des-Arg9-BK) and antagonists (SSR240612 and R-715) were measure …
Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.
Latini A, Pereira PJS, Couture R, Campos MM, Talbot S. Latini A, et al. Oxid Med Cell Longev. 2019 Jan 6;2019:2715326. doi: 10.1155/2019/2715326. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30723534 Free PMC article. No abstract available.
Neurons and Microglia; A Sickly-Sweet Duo in Diabetic Pain Neuropathy.
Rajchgot T, Thomas SC, Wang JC, Ahmadi M, Balood M, Crosson T, Dias JP, Couture R, Claing A, Talbot S. Rajchgot T, et al. Front Neurosci. 2019 Jan 31;13:25. doi: 10.3389/fnins.2019.00025. eCollection 2019. Front Neurosci. 2019. PMID: 30766472 Free PMC article. Review.
Effects of Alpha-Lipoic Acid on Oxidative Stress and Kinin Receptor Expression in Obese Zucker Diabetic Fatty Rats.
Midaoui AE, Talbot S, Lahjouji K, Dias JP, Fantus IG, Couture R. Midaoui AE, et al. J Diabetes Metab. 2015 Jun 1;6(6):1-7. doi: 10.4172/2155-6156.1000556. J Diabetes Metab. 2015. PMID: 26413386 Free PMC article.
Effect of chronic inhibition of nitric oxide on hypertension, insulin resistance, and cardiovascular remodeling in glucose-fed rats.
Pilon M, Wu R, Huot-Marchand JE, deBlois D, Champlain Jd, Couture R. Pilon M, et al. J Cardiovasc Pharmacol. 2009 May;53(5):405-13. doi: 10.1097/FJC.0b013e3181a1d88a. J Cardiovasc Pharmacol. 2009. PMID: 19333132
Bradykinin Type 1 Receptor - Inducible Nitric Oxide Synthase: A New Axis Implicated in Diabetic Retinopathy.
Othman R, Vaucher E, Couture R. Othman R, et al. Front Pharmacol. 2019 Mar 29;10:300. doi: 10.3389/fphar.2019.00300. eCollection 2019. Front Pharmacol. 2019. PMID: 30983997 Free PMC article.
Moreover, the additional increase in vascular permeability in diabetic retina induced by intravitreal injection of R-838, a B1R agonist, was also prevented by 1400W. ...
Moreover, the additional increase in vascular permeability in diabetic retina induced by intravitreal injection of R-838, a B1R agoni …
Activated microglia in the spinal cord underlies diabetic neuropathic pain.
Wang D, Couture R, Hong Y. Wang D, et al. Eur J Pharmacol. 2014 Apr 5;728:59-66. doi: 10.1016/j.ejphar.2014.01.057. Epub 2014 Feb 6. Eur J Pharmacol. 2014. PMID: 24508519 Review.
Kinin receptors in vascular biology and pathology.
Couture R, Blaes N, Girolami JP. Couture R, et al. Curr Vasc Pharmacol. 2014 Mar;12(2):223-48. doi: 10.2174/1570161112666140226121627. Curr Vasc Pharmacol. 2014. PMID: 24568157 Review.
Endogenous kinins are important vasoactive peptides whose effects are mediated by two G-Protein-coupled receptors (R), named B2R (constitutive) and B1R (inducible). ...
Endogenous kinins are important vasoactive peptides whose effects are mediated by two G-Protein-coupled receptors (R), named B2R (con …
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