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A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis.
Doudna JA, Couture S, Szostak JW. Doudna JA, et al. Among authors: couture s. Science. 1991 Mar 29;251(5001):1605-8. doi: 10.1126/science.1707185. Science. 1991. PMID: 1707185
Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns.
Michel F, Ellington AD, Couture S, Szostak JW. Michel F, et al. Among authors: couture s. Nature. 1990 Oct 11;347(6293):578-80. doi: 10.1038/347578a0. Nature. 1990. PMID: 2215683
Mutational analysis of conserved nucleotides in a self-splicing group I intron.
Couture S, Ellington AD, Gerber AS, Cherry JM, Doudna JA, Green R, Hanna M, Pace U, Rajagopal J, Szostak JW. Couture S, et al. J Mol Biol. 1990 Oct 5;215(3):345-58. doi: 10.1016/s0022-2836(05)80356-0. J Mol Biol. 1990. PMID: 1700131
Simultaneous sequencing of coding and noncoding RNA reveals a human transcriptome dominated by a small number of highly expressed noncoding genes.
Boivin V, Deschamps-Francoeur G, Couture S, Nottingham RM, Bouchard-Bourelle P, Lambowitz AM, Scott MS, Abou-Elela S. Boivin V, et al. Among authors: couture s. RNA. 2018 Jul;24(7):950-965. doi: 10.1261/rna.064493.117. Epub 2018 Apr 27. RNA. 2018. PMID: 29703781 Free PMC article.
Tumor microenvironment-associated modifications of alternative splicing.
Brosseau JP, Lucier JF, Nwilati H, Thibault P, Garneau D, Gendron D, Durand M, Couture S, Lapointe E, Prinos P, Klinck R, Perreault JP, Chabot B, Abou-Elela S. Brosseau JP, et al. Among authors: couture s. RNA. 2014 Feb;20(2):189-201. doi: 10.1261/rna.042168.113. Epub 2013 Dec 11. RNA. 2014. PMID: 24335142 Free PMC article.
Identification of discrete classes of small nucleolar RNA featuring different ends and RNA binding protein dependency.
Deschamps-Francoeur G, Garneau D, Dupuis-Sandoval F, Roy A, Frappier M, Catala M, Couture S, Barbe-Marcoux M, Abou-Elela S, Scott MS. Deschamps-Francoeur G, et al. Among authors: couture s. Nucleic Acids Res. 2014 Sep;42(15):10073-85. doi: 10.1093/nar/gku664. Epub 2014 Jul 29. Nucleic Acids Res. 2014. PMID: 25074380 Free PMC article.
Multiple and specific mRNA processing targets for the major human hnRNP proteins.
Venables JP, Koh CS, Froehlich U, Lapointe E, Couture S, Inkel L, Bramard A, Paquet ER, Watier V, Durand M, Lucier JF, Gervais-Bird J, Tremblay K, Prinos P, Klinck R, Elela SA, Chabot B. Venables JP, et al. Among authors: couture s. Mol Cell Biol. 2008 Oct;28(19):6033-43. doi: 10.1128/MCB.00726-08. Epub 2008 Jul 21. Mol Cell Biol. 2008. PMID: 18644864 Free PMC article.
Cancer-associated regulation of alternative splicing.
Venables JP, Klinck R, Koh C, Gervais-Bird J, Bramard A, Inkel L, Durand M, Couture S, Froehlich U, Lapointe E, Lucier JF, Thibault P, Rancourt C, Tremblay K, Prinos P, Chabot B, Elela SA. Venables JP, et al. Among authors: couture s. Nat Struct Mol Biol. 2009 Jun;16(6):670-6. doi: 10.1038/nsmb.1608. Epub 2009 May 17. Nat Struct Mol Biol. 2009. PMID: 19448617
Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.
Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B. Michelle L, et al. Among authors: couture s. Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11. Epub 2011 Dec 27. Mol Cell Biol. 2012. PMID: 22203037 Free PMC article.
Depleting proteins known as core (Y14 and eIF4A3) or auxiliary (RNPS1, Acinus, and SAP18) components of the exon junction complex (EJC) improved the production of the proapoptotic Bcl-x(S) splice variant. ...
Depleting proteins known as core (Y14 and eIF4A3) or auxiliary (RNPS1, Acinus, and SAP18) components of the exon junction complex (EJC) impr …
Alternative splicing of SYK regulates mitosis and cell survival.
Prinos P, Garneau D, Lucier JF, Gendron D, Couture S, Boivin M, Brosseau JP, Lapointe E, Thibault P, Durand M, Tremblay K, Gervais-Bird J, Nwilati H, Klinck R, Chabot B, Perreault JP, Wellinger RJ, Elela SA. Prinos P, et al. Among authors: couture s. Nat Struct Mol Biol. 2011 Jun;18(6):673-9. doi: 10.1038/nsmb.2040. Epub 2011 May 8. Nat Struct Mol Biol. 2011. PMID: 21552259
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