Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

117 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Molecular pharmacology and structure of VPAC Receptors for VIP and PACAP.
Laburthe M, Couvineau A. Laburthe M, et al. Among authors: couvineau a. Regul Pept. 2002 Oct 15;108(2-3):165-73. doi: 10.1016/s0167-0115(02)00099-x. Regul Pept. 2002. PMID: 12220741 Review.
Stimulatory effect of pituitary adenylate cyclase-activating polypeptide 6-38, M65 and vasoactive intestinal polypeptide 6-28 on trigeminal sensory neurons.
Sághy É, Payrits M, Helyes Z, Reglődi D, Bánki E, Tóth G, Couvineau A, Szőke É. Sághy É, et al. Among authors: couvineau a. Neuroscience. 2015 Nov 12;308:144-56. doi: 10.1016/j.neuroscience.2015.08.043. Epub 2015 Aug 28. Neuroscience. 2015. PMID: 26321242
PACAP6-38 was described as a potent PAC1/VPAC2 antagonist in several models, but recent studies reported its agonistic behaviors proposing novel receptorial mechanisms. ...
PACAP6-38 was described as a potent PAC1/VPAC2 antagonist in several models, but recent studies reported its agonistic behaviors prop …
Tryptophan 67 in the human VPAC(1) receptor: crucial role for VIP binding.
Nicole P, Maoret JJ, Couvineau A, Momany FA, Laburthe M. Nicole P, et al. Among authors: couvineau a. Biochem Biophys Res Commun. 2000 Sep 24;276(2):654-9. doi: 10.1006/bbrc.2000.3375. Biochem Biophys Res Commun. 2000. PMID: 11027527
We further investigated this domain by mutating 12 amino acid residues which could participate in the formation of a tight bend (W67) or a coiled coil motif. ...Therefore tryptophan 67 in the human VPAC(1) receptor plays a crucial role in VIP binding due, in …
We further investigated this domain by mutating 12 amino acid residues which could participate in the formation of a tight bend (W67) …
[Directed mutagenesis of human recombinant receptors of vasoactive intestinal peptide of VIP1 and VIP2 type. Difference in structure-activity relationship].
Nicole P, Du K, Couvineau A, Laburthe M. Nicole P, et al. Among authors: couvineau a. Gastroenterol Clin Biol. 1997;21(5):365-9. Gastroenterol Clin Biol. 1997. PMID: 9208011 French.
The S64A mutant showed a 3-fold increase of its dissociation constant as compared to the wild-type receptor. cAMP experiments showed that the E36A mutant mediated a very weak stimulation by VIP. ...This difference in the structure-function relationship should be ins …
The S64A mutant showed a 3-fold increase of its dissociation constant as compared to the wild-type receptor. cAMP experiments showed …
Glycosylation of VIP receptors: a molecular basis for receptor heterogeneity.
Fabre C, el Battari A, Karamanos Y, Couvineau A, Salomon R, Laburthe M, Marvaldi J, Pichon J, Luis J. Fabre C, et al. Among authors: couvineau a. Peptides. 1993 May-Jun;14(3):483-9. doi: 10.1016/0196-9781(93)90136-5. Peptides. 1993. PMID: 8392717
Highly conserved aspartate 68, tryptophane 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP.
Couvineau A, Gaudin P, Maoret JJ, Rouyer-Fessard C, Nicole P, Laburthe M. Couvineau A, et al. Biochem Biophys Res Commun. 1995 Jan 5;206(1):246-52. doi: 10.1006/bbrc.1995.1034. Biochem Biophys Res Commun. 1995. PMID: 7818527
The human VIP receptor belongs to a subfamily of G protein-coupled receptors that includes secretin, glucagon and several other receptors. ...
The human VIP receptor belongs to a subfamily of G protein-coupled receptors that includes secretin, glucagon and several other recep …
Alanine scanning of VIP. Structure-function relationship for binding to human recombinant VPAC1 receptor.
Nicole P, Rouyer-Fessard C, Couvineau A, Drouot C, Fulcrand P, Martinez J, Laburthe M. Nicole P, et al. Among authors: couvineau a. Ann N Y Acad Sci. 2000;921:352-6. doi: 10.1111/j.1749-6632.2000.tb06992.x. Ann N Y Acad Sci. 2000. PMID: 11193851 No abstract available.
The human VPAC1 receptor: three-dimensional model and mutagenesis of the N-terminal domain.
Lins L, Couvineau A, Rouyer-Fessard C, Nicole P, Maoret JJ, Benhamed M, Brasseur R, Thomas A, Laburthe M. Lins L, et al. Among authors: couvineau a. J Biol Chem. 2001 Mar 30;276(13):10153-60. doi: 10.1074/jbc.M009730200. Epub 2000 Dec 21. J Biol Chem. 2001. PMID: 11124960
A subdomain of yeast lipase B was found to have 27% sequence identity and 50% sequence homology with the N-terminal domain (8) of the VPAC(1) receptor together with a good alignment of the hydrophobic clusters. A model of the N-terminal domain of VPAC(1) rece
A subdomain of yeast lipase B was found to have 27% sequence identity and 50% sequence homology with the N-terminal domain (8) of the
Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide.
Nicole P, Lins L, Rouyer-Fessard C, Drouot C, Fulcrand P, Thomas A, Couvineau A, Martinez J, Brasseur R, Laburthe M. Nicole P, et al. Among authors: couvineau a. J Biol Chem. 2000 Aug 4;275(31):24003-12. doi: 10.1074/jbc.M002325200. J Biol Chem. 2000. PMID: 10801840
The data show that substituting residues at 14 positions out of 28 in VIP resulted in a >10-fold increase of K(i) or EC(50) at the VPAC(1) receptor. ...
The data show that substituting residues at 14 positions out of 28 in VIP resulted in a >10-fold increase of K(i) or EC(50) at the …
The human vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor 1 (VPAC1) promoter: characterization and role in receptor expression during enterocytic differentiation of the colon cancer cell line Caco-2Cl.20.
Couvineau A, Maoret JJ, Rouyer-Fessard C, Carrero I, Laburthe M. Couvineau A, et al. Biochem J. 2000 May 1;347 Pt 3(Pt 3):623-32. Biochem J. 2000. PMID: 10769164 Free PMC article.
The minimal promoter region identified encompasses the -205/+76 sequence and contains a crucial CCAAT box (-182/-178) and a GC-rich sequence. Moreover a region (-1348/-933) containing a silencer element was identified. We previously showed that the exp …
The minimal promoter region identified encompasses the -205/+76 sequence and contains a crucial CCAAT box (-182/-178) and a GC …
117 results
Jump to page
Feedback