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Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin.
Xu H, Jiang M, Oetjens M, Bowton EA, Ramirez AH, Jeff JM, Basford MA, Pulley JM, Cowan JD, Wang X, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC. Xu H, et al. Among authors: cowan jd. J Am Med Inform Assoc. 2011 Jul-Aug;18(4):387-91. doi: 10.1136/amiajnl-2011-000208. J Am Med Inform Assoc. 2011. PMID: 21672908 Free PMC article.
The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients.
Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Haas DW. Birdwell KA, et al. Among authors: cowan jd. Pharmacogenet Genomics. 2012 Jan;22(1):32-42. doi: 10.1097/FPC.0b013e32834e1641. Pharmacogenet Genomics. 2012. PMID: 22108237 Free PMC article.
Secondary use of clinical data: the Vanderbilt approach.
Danciu I, Cowan JD, Basford M, Wang X, Saip A, Osgood S, Shirey-Rice J, Kirby J, Harris PA. Danciu I, et al. Among authors: cowan jd. J Biomed Inform. 2014 Dec;52:28-35. doi: 10.1016/j.jbi.2014.02.003. Epub 2014 Feb 14. J Biomed Inform. 2014. PMID: 24534443 Free PMC article.
Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.
Ramirez AH, Shi Y, Schildcrout JS, Delaney JT, Xu H, Oetjens MT, Zuvich RL, Basford MA, Bowton E, Jiang M, Speltz P, Zink R, Cowan J, Pulley JM, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC. Ramirez AH, et al. Pharmacogenomics. 2012 Mar;13(4):407-18. doi: 10.2217/pgs.11.164. Epub 2012 Feb 13. Pharmacogenomics. 2012. PMID: 22329724 Free PMC article.
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future.
Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, Crosslin D, Denny JC, Gallego CJ, Haines JL, Hakonarson H, Harley J, Jarvik GP, Kohane I, Kullo IJ, Larson EB, McCarty C, Ritchie MD, Roden DM, Smith ME, Böttinger EP, Williams MS; eMERGE Network. Gottesman O, et al. Genet Med. 2013 Oct;15(10):761-71. doi: 10.1038/gim.2013.72. Epub 2013 Jun 6. Genet Med. 2013. PMID: 23743551 Free PMC article. Review.
Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping.
Schildcrout JS, Denny JC, Bowton E, Gregg W, Pulley JM, Basford MA, Cowan JD, Xu H, Ramirez AH, Crawford DC, Ritchie MD, Peterson JF, Masys DR, Wilke RA, Roden DM. Schildcrout JS, et al. Among authors: cowan jd. Clin Pharmacol Ther. 2012 Aug;92(2):235-42. doi: 10.1038/clpt.2012.66. Epub 2012 Jun 27. Clin Pharmacol Ther. 2012. PMID: 22739144 Free PMC article.
Biobanks and electronic medical records: enabling cost-effective research.
Bowton E, Field JR, Wang S, Schildcrout JS, Van Driest SL, Delaney JT, Cowan J, Weeke P, Mosley JD, Wells QS, Karnes JH, Shaffer C, Peterson JF, Denny JC, Roden DM, Pulley JM. Bowton E, et al. Among authors: cowan j. Sci Transl Med. 2014 Apr 30;6(234):234cm3. doi: 10.1126/scitranslmed.3008604. Sci Transl Med. 2014. PMID: 24786321 Free PMC article.
A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record.
Karnes JH, Cronin RM, Rollin J, Teumer A, Pouplard C, Shaffer CM, Blanquicett C, Bowton EA, Cowan JD, Mosley JD, Van Driest SL, Weeke PE, Wells QS, Bakchoul T, Denny JC, Greinacher A, Gruel Y, Roden DM. Karnes JH, et al. Among authors: cowan jd. Thromb Haemost. 2015 Apr;113(4):772-81. doi: 10.1160/TH14-08-0670. Epub 2014 Dec 11. Thromb Haemost. 2015. PMID: 25503805 Free PMC article.
94 results