Cowen LE - Search Results

1

Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.

Lou JW, Iyer KR, Hasan SMN, Cowen LE, Mazhab-Jafari MT. Lou JW, et al. Among authors: cowen le. Sci Rep. 2019 Sep 10;9(1):12987. doi: 10.1038/s41598-019-49261-3. Sci Rep. 2019. PMID: 31506493 Free PMC article.

2

Antifungal drug resistance: evolution, mechanisms and impact.

Revie NM, Iyer KR, Robbins N, Cowen LE. Revie NM, et al. Among authors: cowen le. Curr Opin Microbiol. 2018 Oct;45:70-76. doi: 10.1016/j.mib.2018.02.005. Epub 2018 Mar 13. Curr Opin Microbiol. 2018. PMID: 29547801 Free PMC article. Review.

3

Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance.

Kim SH, Iyer KR, Pardeshi L, Muñoz JF, Robbins N, Cuomo CA, Wong KH, Cowen LE. Kim SH, et al. Among authors: cowen le. mBio. 2019 Jan 29;10(1):e02529-18. doi: 10.1128/mBio.02529-18. mBio. 2019. PMID: 30696744 Free PMC article.

4

Erratum for Kim et al., "Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance".

Kim SH, Iyer KR, Pardeshi L, Muñoz JF, Robbins N, Cuomo CA, Wong KH, Cowen LE. Kim SH, et al. Among authors: cowen le. mBio. 2019 Mar 19;10(2):e00346-19. doi: 10.1128/mBio.00346-19. mBio. 2019. PMID: 30890611 Free PMC article. No abstract available.

5

Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2.

Caplan T, Lorente-Macías Á, Stogios PJ, Evdokimova E, Hyde S, Wellington MA, Liston S, Iyer KR, Puumala E, Shekhar-Guturja T, Robbins N, Savchenko A, Krysan DJ, Whitesell L, Zuercher WJ, Cowen LE. Caplan T, et al. Among authors: cowen le. Cell Chem Biol. 2020 Mar 19;27(3):269-282.e5. doi: 10.1016/j.chembiol.2019.12.008. Epub 2020 Jan 7. Cell Chem Biol. 2020. PMID: 31924499 Free PMC article.

6

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris.

Iyer KR, Whitesell L, Porco JA Jr, Henkel T, Brown LE, Robbins N, Cowen LE. Iyer KR, et al. Among authors: cowen le. mBio. 2020 Mar 10;11(2):e03329-19. doi: 10.1128/mBio.03329-19. mBio. 2020. PMID: 32156828 Free PMC article.

7

Flow Cytometric Measurement of Efflux in Candida Species.

Iyer KR, Robbins N, Cowen LE. Iyer KR, et al. Among authors: cowen le. Curr Protoc Microbiol. 2020 Dec;59(1):e121. doi: 10.1002/cpmc.121. Curr Protoc Microbiol. 2020. PMID: 33047867 Free PMC article.

8

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris.

Iyer KR, Camara K, Daniel-Ivad M, Trilles R, Pimentel-Elardo SM, Fossen JL, Marchillo K, Liu Z, Singh S, Muñoz JF, Kim SH, Porco JA Jr, Cuomo CA, Williams NS, Ibrahim AS, Edwards JE Jr, Andes DR, Nodwell JR, Brown LE, Whitesell L, Robbins N, Cowen LE. Iyer KR, et al. Among authors: cowen le. Nat Commun. 2020 Dec 22;11(1):6429. doi: 10.1038/s41467-020-20183-3. Nat Commun. 2020. PMID: 33353950 Free PMC article.

9

Treatment strategies for cryptococcal infection: challenges, advances and future outlook.

Iyer KR, Revie NM, Fu C, Robbins N, Cowen LE. Iyer KR, et al. Among authors: cowen le. Nat Rev Microbiol. 2021 Jul;19(7):454-466. doi: 10.1038/s41579-021-00511-0. Epub 2021 Feb 8. Nat Rev Microbiol. 2021. PMID: 33558691 Free PMC article. Review.

10

Mitochondrial perturbation reduces susceptibility to xenobiotics through altered efflux in Candida albicans.

Hossain S, Veri AO, Liu Z, Iyer KR, O'Meara TR, Robbins N, Cowen LE. Hossain S, et al. Among authors: cowen le. Genetics. 2021 Oct 2;219(2):iyab095. doi: 10.1093/genetics/iyab095. Genetics. 2021. PMID: 34143207 Free PMC article.

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