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78 results
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Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.
Cox TR, Gartland A, Erler JT. Cox TR, et al. Cancer Res. 2016 Jan 15;76(2):188-92. doi: 10.1158/0008-5472.CAN-15-2306. Epub 2016 Jan 5. Cancer Res. 2016. PMID: 26732355 Review.
Lamin A/C is a risk biomarker in colorectal cancer.
Willis ND, Cox TR, Rahman-Casañs SF, Smits K, Przyborski SA, van den Brandt P, van Engeland M, Weijenberg M, Wilson RG, de Bruïne A, Hutchison CJ. Willis ND, et al. Among authors: cox tr. PLoS One. 2008 Aug 20;3(8):e2988. doi: 10.1371/journal.pone.0002988. PLoS One. 2008. PMID: 18714339 Free PMC article.
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ. Erler JT, et al. Among authors: cox tr. Cancer Cell. 2009 Jan 6;15(1):35-44. doi: 10.1016/j.ccr.2008.11.012. Cancer Cell. 2009. PMID: 19111879 Free PMC article.
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A, Erler JT. Barker HE, et al. Among authors: cox tr. Cancer Res. 2011 Mar 1;71(5):1561-72. doi: 10.1158/0008-5472.CAN-10-2868. Epub 2011 Jan 13. Cancer Res. 2011. PMID: 21233336 Free PMC article.
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.
Baker AM, Cox TR, Bird D, Lang G, Murray GI, Sun XF, Southall SM, Wilson JR, Erler JT. Baker AM, et al. Among authors: cox tr. J Natl Cancer Inst. 2011 Mar 2;103(5):407-24. doi: 10.1093/jnci/djq569. Epub 2011 Jan 31. J Natl Cancer Inst. 2011. PMID: 21282564
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.
Baker AM, Bird D, Lang G, Cox TR, Erler JT. Baker AM, et al. Among authors: cox tr. Oncogene. 2013 Apr 4;32(14):1863-8. doi: 10.1038/onc.2012.202. Epub 2012 May 28. Oncogene. 2013. PMID: 22641216
The rationale for targeting the LOX family in cancer.
Barker HE, Cox TR, Erler JT. Barker HE, et al. Among authors: cox tr. Nat Rev Cancer. 2012 Jul 19;12(8):540-52. doi: 10.1038/nrc3319. Nat Rev Cancer. 2012. PMID: 22810810 Review.
Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.
Baker AM, Bird D, Welti JC, Gourlaouen M, Lang G, Murray GI, Reynolds AR, Cox TR, Erler JT. Baker AM, et al. Among authors: cox tr. Cancer Res. 2013 Jan 15;73(2):583-94. doi: 10.1158/0008-5472.CAN-12-2447. Epub 2012 Nov 27. Cancer Res. 2013. PMID: 23188504 Free PMC article.
LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis.
Cox TR, Bird D, Baker AM, Barker HE, Ho MW, Lang G, Erler JT. Cox TR, et al. Cancer Res. 2013 Mar 15;73(6):1721-32. doi: 10.1158/0008-5472.CAN-12-2233. Epub 2013 Jan 23. Cancer Res. 2013. PMID: 23345161 Free PMC article.
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
Chang J, Nicolau MM, Cox TR, Wetterskog D, Martens JW, Barker HE, Erler JT. Chang J, et al. Among authors: cox tr. Breast Cancer Res. 2013;15(4):R67. doi: 10.1186/bcr3461. Breast Cancer Res. 2013. PMID: 23971878 Free PMC article.
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