Crabtree GR - Search Results

1

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin.

Zheng XF, Florentino D, Chen J, Crabtree GR, Schreiber SL. Zheng XF, et al. Among authors: crabtree gr. Cell. 1995 Jul 14;82(1):121-30. doi: 10.1016/0092-8674(95)90058-6. Cell. 1995. PMID: 7606777

2

The mechanism of action of cyclosporin A and FK506.

Schreiber SL, Crabtree GR. Schreiber SL, et al. Among authors: crabtree gr. Immunol Today. 1992 Apr;13(4):136-42. doi: 10.1016/0167-5699(92)90111-J. Immunol Today. 1992. PMID: 1374612 Review.

3

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation.

Clipstone NA, Crabtree GR. Clipstone NA, et al. Among authors: crabtree gr. Nature. 1992 Jun 25;357(6380):695-7. doi: 10.1038/357695a0. Nature. 1992. PMID: 1377362

4

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases.

Chung J, Kuo CJ, Crabtree GR, Blenis J. Chung J, et al. Among authors: crabtree gr. Cell. 1992 Jun 26;69(7):1227-36. doi: 10.1016/0092-8674(92)90643-q. Cell. 1992. PMID: 1377606

5

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase.

Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR. Kuo CJ, et al. Among authors: crabtree gr. Nature. 1992 Jul 2;358(6381):70-3. doi: 10.1038/358070a0. Nature. 1992. PMID: 1614535

6

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A.

Flanagan WM, Corthésy B, Bram RJ, Crabtree GR. Flanagan WM, et al. Among authors: crabtree gr. Nature. 1991 Aug 29;352(6338):803-7. doi: 10.1038/352803a0. Nature. 1991. PMID: 1715516

7

Site of action of cyclosporine and FK 506 in the pathways of communication between the T-lymphocyte antigen receptor and the early activation genes.

Ullman KS, Flanagan WM, Cothesy B, Kuo P, Northrop JP, Crabtree GR. Ullman KS, et al. Among authors: crabtree gr. Transplant Proc. 1991 Dec;23(6):2845. Transplant Proc. 1991. PMID: 1721294 Review. No abstract available.

8

A transcriptional hierarchy involved in mammalian cell-type specification.

Kuo CJ, Conley PB, Chen L, Sladek FM, Darnell JE Jr, Crabtree GR. Kuo CJ, et al. Among authors: crabtree gr. Nature. 1992 Jan 30;355(6359):457-61. doi: 10.1038/355457a0. Nature. 1992. PMID: 1734282

9

Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein.

Mendel DB, Khavari PA, Conley PB, Graves MK, Hansen LP, Admon A, Crabtree GR. Mendel DB, et al. Among authors: crabtree gr. Science. 1991 Dec 20;254(5039):1762-7. doi: 10.1126/science.1763325. Science. 1991. PMID: 1763325

10

HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro.

Mendel DB, Hansen LP, Graves MK, Conley PB, Crabtree GR. Mendel DB, et al. Among authors: crabtree gr. Genes Dev. 1991 Jun;5(6):1042-56. doi: 10.1101/gad.5.6.1042. Genes Dev. 1991. PMID: 2044952

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