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Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures.
Kazim SF, Sharma A, Saroja SR, Seo JH, Larson CS, Ramakrishnan A, Wang M, Blitzer RD, Shen L, Peña CJ, Crary JF, Shimoda LA, Zhang B, Nestler EJ, Pereira AC. Kazim SF, et al. Among authors: crary jf. Biol Psychiatry. 2022 Feb 15;91(4):346-358. doi: 10.1016/j.biopsych.2021.02.973. Epub 2021 Mar 24. Biol Psychiatry. 2022. PMID: 34130857 Free PMC article.
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.
Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B. Wang M, et al. Among authors: crary jf. Genome Med. 2016 Nov 1;8(1):104. doi: 10.1186/s13073-016-0355-3. Genome Med. 2016. PMID: 27799057 Free PMC article.
Tau Phosphorylation and Aggregation in the Developing Human Brain.
Hefti MM, Kim S, Bell AJ, Betters RK, Fiock KL, Iida MA, Smalley ME, Farrell K, Fowkes ME, Crary JF. Hefti MM, et al. Among authors: crary jf. J Neuropathol Exp Neurol. 2019 Oct 1;78(10):930-938. doi: 10.1093/jnen/nlz073. J Neuropathol Exp Neurol. 2019. PMID: 31504677 Free PMC article.
Evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy.
Cherry JD, Kim SH, Stein TD, Pothast MJ, Nicks R, Meng G, Huber BR, Mez J, Alosco ML, Tripodis Y, Farrell K, Alvarez VE, McKee AC, Crary JF. Cherry JD, et al. Among authors: crary jf. Brain Pathol. 2020 Sep;30(5):913-925. doi: 10.1111/bpa.12867. Epub 2020 Jul 2. Brain Pathol. 2020. PMID: 32500646 Free PMC article.
Tau Isoform Profile in Essential Tremor Diverges From Other Tauopathies.
Kim SH, Farrell K, Cosentino S, Vonsattel JG, Faust PL, Cortes EP, Bennet DA, Louis ED, Crary JF. Kim SH, et al. Among authors: crary jf. J Neuropathol Exp Neurol. 2021 Sep 27;80(9):835-843. doi: 10.1093/jnen/nlab073. J Neuropathol Exp Neurol. 2021. PMID: 34363663 Free PMC article.
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells.
Navarro E, Udine E, de Paiva Lopes K, Parks M, Riboldi G, Schilder BM, Humphrey J, Snijders GJL, Vialle RA, Zhuang M, Sikder T, Argyrou C, Allan A, Chao MJ, Farrell K, Henderson B, Simon S, Raymond D, Elango S, Ortega RA, Shanker V, Swan M, Zhu CW, Ramdhani R, Walker RH, Tse W, Sano M, Pereira AC, Ahfeldt T, Goate AM, Bressman S, Crary JF, de Witte L, Frucht S, Saunders-Pullman R, Raj T. Navarro E, et al. Among authors: crary jf. Nat Aging. 2021 Sep;1(9):850-863. doi: 10.1038/s43587-021-00110-x. Epub 2021 Sep 14. Nat Aging. 2021. PMID: 35005630 Free PMC article.
Histopathologic brain age estimation via multiple instance learning.
Marx GA, Kauffman J, McKenzie AT, Koenigsberg DG, McMillan CT, Morgello S, Karlovich E, Insausti R, Richardson TE, Walker JM, White CL 3rd, Babrowicz BM, Shen L, McKee AC, Stein TD; PART Working Group; Farrell K, Crary JF. Marx GA, et al. Among authors: crary jf. Acta Neuropathol. 2023 Dec;146(6):785-802. doi: 10.1007/s00401-023-02636-3. Epub 2023 Oct 10. Acta Neuropathol. 2023. PMID: 37815677 Free PMC article.
Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson's disease.
Wang Q, Wang M, Choi I, Sarrafha L, Liang M, Ho L, Farrell K, Beaumont KG, Sebra R, De Sanctis C, Crary JF, Ahfeldt T, Blanchard J, Neavin D, Powell J, Davis DA, Sun X, Zhang B, Yue Z. Wang Q, et al. Among authors: crary jf. Sci Adv. 2024 Jan 12;10(2):eadi8287. doi: 10.1126/sciadv.adi8287. Epub 2024 Jan 10. Sci Adv. 2024. PMID: 38198537 Free PMC article.
133 results