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706 results

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Function and health-related quality of life: results from a randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis. Leflunomide Rheumatoid Arthritis Investigators Group.
Strand V, Tugwell P, Bombardier C, Maetzel A, Crawford B, Dorrier C, Thompson A, Wells G. Strand V, et al. Among authors: crawford b. Arthritis Rheum. 1999 Sep;42(9):1870-8. doi: 10.1002/1529-0131(199909)42:9<1870::AID-ANR11>3.0.CO;2-D. Arthritis Rheum. 1999. PMID: 10513801 Free article. Clinical Trial.
Clinical improvement as reflected in measures of function and health-related quality of life following treatment with leflunomide compared with methotrexate in patients with rheumatoid arthritis: sensitivity and relative efficiency to detect a treatment effect in a twelve-month, placebo-controlled trial. Leflunomide Rheumatoid Arthritis Investigators Group.
Tugwell P, Wells G, Strand V, Maetzel A, Bombardier C, Crawford B, Dorrier C, Thompson A. Tugwell P, et al. Among authors: crawford b. Arthritis Rheum. 2000 Mar;43(3):506-14. doi: 10.1002/1529-0131(200003)43:3<506::AID-ANR5>3.0.CO;2-U. Arthritis Rheum. 2000. PMID: 10728742 Free article. Clinical Trial.
Physical function and health related quality of life: analysis of 2-year data from randomized, controlled studies of leflunomide, sulfasalazine, or methotrexate in patients with active rheumatoid arthritis.
Strand V, Scott DL, Emery P, Kalden JR, Smolen JS, Cannon GW, Tugwell P, Crawford B; Leflunomide Rheumatoid Arthritis Investigators Groups. Strand V, et al. Among authors: crawford b. J Rheumatol. 2005 Apr;32(4):590-601. J Rheumatol. 2005. PMID: 15801012
An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in a rheumatoid arthritis clinical trial.
Pincus T, Strand V, Koch G, Amara I, Crawford B, Wolfe F, Cohen S, Felson D. Pincus T, et al. Among authors: crawford b. Arthritis Rheum. 2003 Mar;48(3):625-30. doi: 10.1002/art.10824. Arthritis Rheum. 2003. PMID: 12632413 Free article. Clinical Trial.
Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial.
Kremer JM, Genovese MC, Cannon GW, Caldwell JR, Cush JJ, Furst DE, Luggen ME, Keystone E, Weisman MH, Bensen WM, Kaine JL, Ruderman EM, Coleman P, Curtis DL, Kopp EJ, Kantor SM, Waltuck J, Lindsley HB, Markenson JA, Strand V, Crawford B, Fernando I, Simpson K, Bathon JM. Kremer JM, et al. Among authors: crawford b. Ann Intern Med. 2002 Nov 5;137(9):726-33. doi: 10.7326/0003-4819-137-9-200211050-00007. Ann Intern Med. 2002. PMID: 12416946 Clinical Trial.
Combination leflunomide and methotrexate (MTX) therapy for patients with active rheumatoid arthritis failing MTX monotherapy: open-label extension of a randomized, double-blind, placebo controlled trial.
Kremer J, Genovese M, Cannon GW, Caldwell J, Cush J, Furst DE, Luggen M, Keystone E, Bathon J, Kavanaugh A, Ruderman E, Coleman P, Curtis D, Kopp E, Kantor S, Weisman M, Waltuck J, Lindsley HB, Markenson J, Crawford B, Fernando I, Simpson K, Strand V. Kremer J, et al. Among authors: crawford b. J Rheumatol. 2004 Aug;31(8):1521-31. J Rheumatol. 2004. PMID: 15290730 Clinical Trial.
706 results