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Proof-of-concept studies with a computationally designed Mpro inhibitor as a synergistic combination regimen alternative to Paxlovid.
Papini C, Ullah I, Ranjan AP, Zhang S, Wu Q, Spasov KA, Zhang C, Mothes W, Crawford JM, Lindenbach BD, Uchil PD, Kumar P, Jorgensen WL, Anderson KS. Papini C, et al. Among authors: crawford jm. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2320713121. doi: 10.1073/pnas.2320713121. Epub 2024 Apr 15. Proc Natl Acad Sci U S A. 2024. PMID: 38621119 Free article.
IL-10 constrains sphingolipid metabolism to limit inflammation.
York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. York AG, et al. Among authors: crawford jm. Nature. 2024 Mar;627(8004):628-635. doi: 10.1038/s41586-024-07098-5. Epub 2024 Feb 21. Nature. 2024. PMID: 38383790 Free PMC article.
Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis.
Xiang X, Bhowmick K, Shetty K, Ohshiro K, Yang X, Wong LL, Yu H, Latham PS, Satapathy SK, Brennan C, Dima RJ, Chambwe N, Sharifova G, Cacaj F, John S, Crawford JM, Huang H, Dasarathy S, Krainer AR, He AR, Amdur RL, Mishra L. Xiang X, et al. Among authors: crawford jm. Genes Cancer. 2024 Feb 1;15:1-14. doi: 10.18632/genesandcancer.234. eCollection 2024. Genes Cancer. 2024. PMID: 38323119 Free PMC article.
Bioactivity and efficacy of a hyperimmune bovine colostrum product- Travelan, against shigellosis in a non-Human primate model (Macaca mulatta).
Islam D, Ruamsap N, Imerbsin R, Khanijou P, Gonwong S, Wegner MD, McVeigh A, Poly FM, Crawford JM, Swierczewski BE, Kaminski RW, Laird RM. Islam D, et al. Among authors: crawford jm. PLoS One. 2023 Dec 13;18(12):e0294021. doi: 10.1371/journal.pone.0294021. eCollection 2023. PLoS One. 2023. PMID: 38091314 Free PMC article.
Clinical Utility of SARS-CoV-2 Serological Testing and Defining a Correlate of Protection.
Sobhani K, Cheng S, Binder RA, Mantis NJ, Crawford JM, Okoye N, Braun JG, Joung S, Wang M, Lozanski G, King CL, Roback JD, Granger DA, Boppana SB, Karger AB. Sobhani K, et al. Among authors: crawford jm. Vaccines (Basel). 2023 Oct 26;11(11):1644. doi: 10.3390/vaccines11111644. Vaccines (Basel). 2023. PMID: 38005976 Free PMC article. Review.
489 results