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The presynaptic component of the serotonergic system is required for clozapine's efficacy.
Yadav PN, Abbas AI, Farrell MS, Setola V, Sciaky N, Huang XP, Kroeze WK, Crawford LK, Piel DA, Keiser MJ, Irwin JJ, Shoichet BK, Deneris ES, Gingrich J, Beck SG, Roth BL. Yadav PN, et al. Among authors: crawford lk. Neuropsychopharmacology. 2011 Feb;36(3):638-51. doi: 10.1038/npp.2010.195. Epub 2010 Nov 3. Neuropsychopharmacology. 2011. PMID: 21048700 Free PMC article.
Astrocytes contribute to pain gating in the spinal cord.
Xu Q, Ford NC, He S, Huang Q, Anderson M, Chen Z, Yang F, Crawford LK, Caterina MJ, Guan Y, Dong X. Xu Q, et al. Among authors: crawford lk. Sci Adv. 2021 Nov 5;7(45):eabi6287. doi: 10.1126/sciadv.abi6287. Epub 2021 Nov 3. Sci Adv. 2021. PMID: 34730998 Free PMC article.
In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure exacerbates urinary dysfunction in hormone-treated C57BL/6J mice through a non-malignant mechanism involving proteomic changes in the prostate that differ from those elicited by testosterone and estradiol.
Turco AE, Thomas S, Crawford LK, Tang W, Peterson RE, Li L, Ricke WA, Vezina CM. Turco AE, et al. Among authors: crawford lk. Am J Clin Exp Urol. 2020 Feb 25;8(1):59-72. eCollection 2020. Am J Clin Exp Urol. 2020. PMID: 32211455 Free PMC article.
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