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Clinical trial results of peginterferons in combination with ribavirin.
Craxi A, Licata A. Craxi A, et al. Semin Liver Dis. 2003;23 Suppl 1:35-46. doi: 10.1055/s-2003-41633. Semin Liver Dis. 2003. PMID: 12934167 Review.
Patients with genotype 1 infection have a 42 to 51% likelihood of response to 48 weeks of therapy. Those with genotypes 2 or 3 infection will respond to 24 weeks of therapy in 78 to 82% of cases. ...A SVR after retreatment of relapsers and nonresponders with PEG-IFN …
Patients with genotype 1 infection have a 42 to 51% likelihood of response to 48 weeks of therapy. Those with genotypes 2 or 3 infect …
Serum hepatitis C virus (HCV)-RNA and response to alpha-interferon in anti-HCV positive chronic hepatitis.
Magrin S, Craxì A, Fabiano C, Fiorentino G, Marino L, Almasio P, Pinzello GB, Palazzo U, Vitale M, Maggio A, et al. Magrin S, et al. Among authors: craxi a. J Med Virol. 1992 Nov;38(3):200-6. doi: 10.1002/jmv.1890380309. J Med Virol. 1992. PMID: 1283753
PCR primers from the 5'-noncoding (NC) region were more sensitive than primers from a non-structural (NS5) region in detecting HCV-RNA (21/22, 95% vs. 7/22, 32%, respectively). ...
PCR primers from the 5'-noncoding (NC) region were more sensitive than primers from a non-structural (NS5) region in detecting HCV-RN …
Hepatitis delta superinfection during alpha-interferon treatment for hepatitis B.
Craxì A, Di Marco V, Bruno R, Fabiano C. Craxì A, et al. Ital J Gastroenterol. 1992 Jan;24(1):19-20; discussion 20-1. Ital J Gastroenterol. 1992. PMID: 1571575
We report the case of a young, immunocompetent HBsAg carrier in whom hepatitis Delta virus superinfection occurred while he was receiving alpha-interferon in order to reduce high level HBV replication, and followed a peculiar course....
We report the case of a young, immunocompetent HBsAg carrier in whom hepatitis Delta virus superinfection occurred while he was recei …
Is autoimmune chronic active hepatitis a HCV-related disease?
Magrin S, Craxì A, Fiorentino G, Fabiano C, Provenzano G, Pinzello GB, Palazzo U, Almasio P, Pagliaro L. Magrin S, et al. Among authors: craxi a. J Hepatol. 1991 Jul;13(1):56-60. doi: 10.1016/0168-8278(91)90864-8. J Hepatol. 1991. PMID: 1717543
An ELISA anti-HCV test and a recombinant immunoblot assay (RIBA-HCV) were used. Thirteen patients (59%) were anti-HCV positive and five (23%) anti-HCV negative by both ELISA and RIBA-HCV tests. ...False positive for anti-HCV (i.e., a positive ELISA test not confirme …
An ELISA anti-HCV test and a recombinant immunoblot assay (RIBA-HCV) were used. Thirteen patients (59%) were anti-HCV positive and fi …
Hepatitis C virus replication in 'autoimmune' chronic hepatitis.
Magrin S, Craxi A, Fabiano C, Fiorentino G, Almasio P, Palazzo U, Pinzello G, Provenzano G, Pagliaro L, Choo QL, et al. Magrin S, et al. Among authors: craxi a. J Hepatol. 1991 Nov;13(3):364-7. doi: 10.1016/0168-8278(91)90082-m. J Hepatol. 1991. PMID: 1725529
Thus, a subgroup of autoantibody-positive chronic active hepatitis can be recognized as HCV-related and should be clinically and etiologically distinguished from autoimmune chronic active hepatitis. ...
Thus, a subgroup of autoantibody-positive chronic active hepatitis can be recognized as HCV-related and should be clinically and etio …
Hepatitis C virus antibodies in chronic liver diseases of different aetiology.
Craxi A, Almasio P, Di Marco V, Magrin S, Bruno R, Cammà C, Fiorentino G, Lo Jacono O, Marino L, Palazzo U, et al. Craxi A, et al. Ital J Gastroenterol. 1991 Jun;23(5):244-8. Ital J Gastroenterol. 1991. PMID: 1742513
Subjects with CLD and a history of parenteral exposure are almost always anti-HCV positive (89.2%). Patients with HBV-related CLD and previous drug-addicts are on the average younger than other disease groups, irrespective of their HCV status. Among subjects whose CLD is r …
Subjects with CLD and a history of parenteral exposure are almost always anti-HCV positive (89.2%). Patients with HBV-related CLD and …
Recombinant interferon alpha-2B for acute post-transfusion hepatitis in acute myeloid leukemia.
Almasio P, Mirto S, Malleo C, Di Marco V, Caronia F, Craxi A. Almasio P, et al. Among authors: craxi a. Haematologica. 1991 Sep-Oct;76(5):429-30. Haematologica. 1991. PMID: 1806450 Clinical Trial.
Post-transfusion hepatitis (PTH) is a major problem in patients with acute leukemias requiring blood products during induction or consolidation therapy. ...In order to assess the efficacy and safety of a short course of alpha-interferon (alpha-IFN) in inducing early …
Post-transfusion hepatitis (PTH) is a major problem in patients with acute leukemias requiring blood products during induction or con …
Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomised clinical trials.
Tinè F, Magrin S, Craxì A, Pagliaro L. Tinè F, et al. Among authors: craxi a. J Hepatol. 1991 Sep;13(2):192-9. doi: 10.1016/0168-8278(91)90814-r. J Hepatol. 1991. PMID: 1835989 Clinical Trial.
We reviewed randomised clinical trials evaluating the effect of lymphoblastoid or recombinant alpha-interferon in non-A, non-B chronic hepatitis. ...We conclude that larger trials are needed to identify an optimal schedule of treatment and to evaluate predictors of interfe …
We reviewed randomised clinical trials evaluating the effect of lymphoblastoid or recombinant alpha-interferon in non-A, non-B chroni …
Treatment with recombinant alpha 2b-interferon of chronic HDV hepatitis in children.
Craxì A, Di Marco V, Volpes R, Marra S, Rizzetto M, Rosina F, Barbera C, Bortolotti F, Crivellaro C, Iannuzzi C, et al. Craxì A, et al. Prog Clin Biol Res. 1991;364:399-404. Prog Clin Biol Res. 1991. PMID: 2020715 No abstract available.
Anti-alpha interferon antibodies after alpha interferon treatment in patients with chronic viral hepatitis.
Craxi A, Di Marco V, Volpes R, Palazzo U. Craxi A, et al. Hepatogastroenterology. 1988 Dec;35(6):304-5. Hepatogastroenterology. 1988. PMID: 3063647
Thirty-five patients with chronic viral hepatitis (B, D or non A, non B), treated with alpha interferon were evaluated by a highly sensitive enzyme immunoassay for the presence of alpha interferon neutralizing antibodies before and after three months of treatment. . …
Thirty-five patients with chronic viral hepatitis (B, D or non A, non B), treated with alpha interferon were evaluated by a hi …
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