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Circular RNAs open a new chapter in cardiovascular biology.
Aufiero S, Reckman YJ, Pinto YM, Creemers EE. Aufiero S, et al. Among authors: creemers ee. Nat Rev Cardiol. 2019 Aug;16(8):503-514. doi: 10.1038/s41569-019-0185-2. Nat Rev Cardiol. 2019. PMID: 30952956 Review.
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Heymans S, Luttun A, Nuyens D, Theilmeier G, Creemers E, Moons L, Dyspersin GD, Cleutjens JP, Shipley M, Angellilo A, Levi M, NĂ¼be O, Baker A, Keshet E, Lupu F, Herbert JM, Smits JF, Shapiro SD, Baes M, Borgers M, Collen D, Daemen MJ, Carmeliet P. Heymans S, et al. Nat Med. 1999 Oct;5(10):1135-42. doi: 10.1038/13459. Nat Med. 1999. PMID: 10502816
Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction.
Creemers E, Cleutjens J, Smits J, Heymans S, Moons L, Collen D, Daemen M, Carmeliet P. Creemers E, et al. Am J Pathol. 2000 Jun;156(6):1865-73. doi: 10.1016/S0002-9440(10)65060-2. Am J Pathol. 2000. PMID: 10854210 Free PMC article.
Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice.
Blankesteijn WM, Creemers E, Lutgens E, Cleutjens JP, Daemen MJ, Smits JF. Blankesteijn WM, et al. Acta Physiol Scand. 2001 Sep;173(1):75-82. doi: 10.1046/j.1365-201X.2001.00887.x. Acta Physiol Scand. 2001. PMID: 11678729 Review.
Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice.
Creemers EE, Davis JN, Parkhurst AM, Leenders P, Dowdy KB, Hapke E, Hauet AM, Escobar PG, Cleutjens JP, Smits JF, Daemen MJ, Zile MR, Spinale FG. Creemers EE, et al. Am J Physiol Heart Circ Physiol. 2003 Jan;284(1):H364-71. doi: 10.1152/ajpheart.00511.2002. Epub 2002 Sep 26. Am J Physiol Heart Circ Physiol. 2003. PMID: 12388239
Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction.
van den Borne SW, Cleutjens JP, Hanemaaijer R, Creemers EE, Smits JF, Daemen MJ, Blankesteijn WM. van den Borne SW, et al. Cardiovasc Pathol. 2009 Jan-Feb;18(1):37-43. doi: 10.1016/j.carpath.2007.12.012. Epub 2008 Mar 4. Cardiovasc Pathol. 2009. PMID: 18402833
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling.
Duisters RF, Tijsen AJ, Schroen B, Leenders JJ, Lentink V, van der Made I, Herias V, van Leeuwen RE, Schellings MW, Barenbrug P, Maessen JG, Heymans S, Pinto YM, Creemers EE. Duisters RF, et al. Circ Res. 2009 Jan 30;104(2):170-8, 6p following 178. doi: 10.1161/CIRCRESAHA.108.182535. Epub 2008 Dec 18. Circ Res. 2009. PMID: 19096030
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