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Regulation and functions of the IL-10 family of cytokines in inflammation and disease.
Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG. Ouyang W, et al. Among authors: crellin nk. Annu Rev Immunol. 2011;29:71-109. doi: 10.1146/annurev-immunol-031210-101312. Annu Rev Immunol. 2011. PMID: 21166540 Review.
IL-2: Change Structure … Change Function.
Bluestone JA, Crellin N, Trotta E. Bluestone JA, et al. Immunity. 2015 May 19;42(5):779-81. doi: 10.1016/j.immuni.2015.05.002. Immunity. 2015. PMID: 25992850
The IL-17 pathway as a major therapeutic target in autoimmune diseases.
Hu Y, Shen F, Crellin NK, Ouyang W. Hu Y, et al. Among authors: crellin nk. Ann N Y Acad Sci. 2011 Jan;1217:60-76. doi: 10.1111/j.1749-6632.2010.05825.x. Epub 2010 Dec 13. Ann N Y Acad Sci. 2011. PMID: 21155836 Review.
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161.
Mjösberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B, Fokkens WJ, Cupedo T, Spits H. Mjösberg JM, et al. Among authors: crellin nk. Nat Immunol. 2011 Sep 11;12(11):1055-62. doi: 10.1038/ni.2104. Nat Immunol. 2011. PMID: 21909091
IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium.
Ota N, Wong K, Valdez PA, Zheng Y, Crellin NK, Diehl L, Ouyang W. Ota N, et al. Among authors: crellin nk. Nat Immunol. 2011 Aug 28;12(10):941-8. doi: 10.1038/ni.2089. Nat Immunol. 2011. PMID: 21874025
Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2.
Crellin NK, Trifari S, Kaplan CD, Satoh-Takayama N, Di Santo JP, Spits H. Crellin NK, et al. Immunity. 2010 Nov 24;33(5):752-64. doi: 10.1016/j.immuni.2010.10.012. Epub 2010 Nov 4. Immunity. 2010. PMID: 21055975 Free article.
Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells.
Crellin NK, Trifari S, Kaplan CD, Cupedo T, Spits H. Crellin NK, et al. J Exp Med. 2010 Feb 15;207(2):281-90. doi: 10.1084/jem.20091509. Epub 2010 Feb 8. J Exp Med. 2010. PMID: 20142432 Free PMC article.
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells.
Cupedo T, Crellin NK, Papazian N, Rombouts EJ, Weijer K, Grogan JL, Fibbe WE, Cornelissen JJ, Spits H. Cupedo T, et al. Among authors: crellin nk. Nat Immunol. 2009 Jan;10(1):66-74. doi: 10.1038/ni.1668. Epub 2008 Nov 23. Nat Immunol. 2009. PMID: 19029905
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells.
Trifari S, Kaplan CD, Tran EH, Crellin NK, Spits H. Trifari S, et al. Among authors: crellin nk. Nat Immunol. 2009 Aug;10(8):864-71. doi: 10.1038/ni.1770. Epub 2009 Jul 5. Nat Immunol. 2009. PMID: 19578368
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.
Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA. Trotta E, et al. Among authors: crellin nk. Nat Med. 2018 Jul;24(7):1005-1014. doi: 10.1038/s41591-018-0070-2. Epub 2018 Jun 25. Nat Med. 2018. PMID: 29942088 Free PMC article.
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