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Page 1
Predicting base editing outcomes using position-specific sequence determinants.
Pallaseni A, Peets EM, Koeppel J, Weller J, Vanderstichele T, Ho UL, Crepaldi L, van Leeuwen J, Allen F, Parts L. Pallaseni A, et al. Among authors: crepaldi l. Nucleic Acids Res. 2022 Apr 8;50(6):3551-3564. doi: 10.1093/nar/gkac161. Nucleic Acids Res. 2022. PMID: 35286377 Free PMC article.
Predicting the mutations generated by repair of Cas9-induced double-strand breaks.
Allen F, Crepaldi L, Alsinet C, Strong AJ, Kleshchevnikov V, De Angeli P, Páleníková P, Khodak A, Kiselev V, Kosicki M, Bassett AR, Harding H, Galanty Y, Muñoz-Martínez F, Metzakopian E, Jackson SP, Parts L. Allen F, et al. Among authors: crepaldi l. Nat Biotechnol. 2018 Nov 27:10.1038/nbt.4317. doi: 10.1038/nbt.4317. Online ahead of print. Nat Biotechnol. 2018. PMID: 30480667 Free PMC article.
Optimized whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells.
Usluer S, Hallast P, Crepaldi L, Zhou Y, Urgo K, Dincer C, Su J, Noell G, Alasoo K, El Garwany O, Gerety SS, Newman B, Dovey OM, Parts L. Usluer S, et al. Among authors: crepaldi l. Stem Cell Reports. 2023 May 9;18(5):1061-1074. doi: 10.1016/j.stemcr.2023.03.008. Epub 2023 Apr 6. Stem Cell Reports. 2023. PMID: 37028423 Free PMC article.
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations.
Pallaseni A, Peets EM, Girling G, Crepaldi L, Kuzmin I, Moor M, Muñoz-Subirana N, Schimmel J, Serçin Ö, Mardin BR, Tijsterman M, Peterson H, Kosicki M, Parts L. Pallaseni A, et al. Among authors: crepaldi l. bioRxiv [Preprint]. 2024 Sep 14:2023.06.28.546891. doi: 10.1101/2023.06.28.546891. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 27;15(1):10271. doi: 10.1038/s41467-024-54566-7. PMID: 37425722 Free PMC article. Updated. Preprint.
Enhanced citrate consumption increases colon permeability in C57BL/6J mice by affecting gut microbiota and activating HIF-1α.
Costa-Bartuli E, Paixão LP, Crepaldi LD, da Fonseca R, Vianna M, Moraes-Ribeiro R, Lima GV, Nascimento Junior JXD, Branco JR, Caldas CAG, Belo TCA, Takiya CM, de Almeida LA, Zancan P, Sola-Penna M. Costa-Bartuli E, et al. Among authors: crepaldi ld. J Nutr Biochem. 2025 Sep;143:109942. doi: 10.1016/j.jnutbio.2025.109942. Epub 2025 May 2. J Nutr Biochem. 2025. PMID: 40320183
Cosmetic Therapeutic Keratopigmentation.
Trindade BLC, Coelho IB, Magalhães LL, Crepaldi LA, Man Fu FM, Da Glória LMR. Trindade BLC, et al. Among authors: crepaldi la. Clin Ophthalmol. 2025 Feb 13;19:527-534. doi: 10.2147/OPTH.S507490. eCollection 2025. Clin Ophthalmol. 2025. PMID: 39967784 Free PMC article.
Dietary caloric input and tumor growth accelerate senescence and modulate liver and adipose tissue crosstalk.
Nascimento Júnior JXD, Gomes JDC, Imbroisi Filho R, Valença HM, Branco JR, Araújo AB, Moreira AOE, Crepaldi LD, Paixão LP, Ochioni AC, Demaria TM, Leandro JGB, Casanova LM, Sola-Penna M, Zancan P. Nascimento Júnior JXD, et al. Among authors: crepaldi ld. Commun Biol. 2025 Jan 7;8(1):18. doi: 10.1038/s42003-025-07451-y. Commun Biol. 2025. PMID: 39775048 Free PMC article.
Temperature control during pars plana vitrectomy.
Romano MR, Barachetti L, Ferrara M, Mauro A, Crepaldi L, Bronzo V, Franzo G, Ravasio G, Giudice C. Romano MR, et al. Among authors: crepaldi l. Graefes Arch Clin Exp Ophthalmol. 2025 Feb;263(2):425-435. doi: 10.1007/s00417-024-06631-6. Epub 2024 Sep 9. Graefes Arch Clin Exp Ophthalmol. 2025. PMID: 39249514
62 results