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A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma.
Laks DR, Oses-Prieto JA, Alvarado AG, Nakashima J, Chand S, Azzam DB, Gholkar AA, Sperry J, Ludwig K, Condro MC, Nazarian S, Cardenas A, Shih MYS, Damoiseaux R, France B, Orozco N, Visnyei K, Crisman TJ, Gao F, Torres JZ, Coppola G, Burlingame AL, Kornblum HI. Laks DR, et al. Among authors: crisman tj. Neuro Oncol. 2018 May 18;20(6):764-775. doi: 10.1093/neuonc/nox215. Neuro Oncol. 2018. PMID: 29136244 Free PMC article.
Large-scale assessment of the gliomasphere model system.
Laks DR, Crisman TJ, Shih MY, Mottahedeh J, Gao F, Sperry J, Garrett MC, Yong WH, Cloughesy TF, Liau LM, Lai A, Coppola G, Kornblum HI. Laks DR, et al. Among authors: crisman tj. Neuro Oncol. 2016 Oct;18(10):1367-78. doi: 10.1093/neuonc/now045. Epub 2016 Apr 25. Neuro Oncol. 2016. PMID: 27116978 Free PMC article.
Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS.
Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett LB, Singh B, Lee S, Crisman T, Gao F, Li S, Kapur K, Geschwind DH, Kosik KS, Coppola G, He Z, Carmichael ST, Benowitz LI, Costigan M, Woolf CJ. Omura T, et al. Neuron. 2015 Jun 3;86(5):1215-27. doi: 10.1016/j.neuron.2015.05.005. Epub 2015 May 21. Neuron. 2015. PMID: 26004914 Free PMC article.
Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS.
Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett LB, Singh B, Lee S, Crisman T, Gao F, Li S, Kapur K, Geschwind DH, Kosik KS, Coppola G, He Z, Carmichael ST, Benowitz LI, Costigan M, Woolf CJ. Omura T, et al. Neuron. 2016 May 4;90(3):662. doi: 10.1016/j.neuron.2016.04.025. Neuron. 2016. PMID: 27151643 Free PMC article. No abstract available.
Which aspects of HTS are empirically correlated with downstream success?
Bender A, Bojanic D, Davies JW, Crisman TJ, Mikhailov D, Scheiber J, Jenkins JL, Deng Z, Hill WA, Popov M, Jacoby E, Glick M. Bender A, et al. Among authors: crisman tj. Curr Opin Drug Discov Devel. 2008 May;11(3):327-37. Curr Opin Drug Discov Devel. 2008. PMID: 18428086 Review.
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