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Why does cytotoxic chemotherapy cure only some cancers?
Savage P, Stebbing J, Bower M, Crook T. Savage P, et al. Among authors: crook t. Nat Clin Pract Oncol. 2009 Jan;6(1):43-52. doi: 10.1038/ncponc1260. Epub 2008 Nov 4. Nat Clin Pract Oncol. 2009. PMID: 18982000 Review.
Cytotoxic-free treatment designs: time to resistance.
Stebbing J, Crook T. Stebbing J, et al. Among authors: crook t. Nat Clin Pract Oncol. 2007 Jan;4(1):1. doi: 10.1038/ncponc0695. Nat Clin Pract Oncol. 2007. PMID: 17183347 No abstract available.
Yes-associated protein (YAP) functions as a tumor suppressor in breast.
Yuan M, Tomlinson V, Lara R, Holliday D, Chelala C, Harada T, Gangeswaran R, Manson-Bishop C, Smith P, Danovi SA, Pardo O, Crook T, Mein CA, Lemoine NR, Jones LJ, Basu S. Yuan M, et al. Among authors: crook t. Cell Death Differ. 2008 Nov;15(11):1752-9. doi: 10.1038/cdd.2008.108. Epub 2008 Jul 11. Cell Death Differ. 2008. PMID: 18617895
p73 is over-expressed in vulval cancer principally as the Delta 2 isoform.
O'Nions J, Brooks LA, Sullivan A, Bell A, Dunne B, Rozycka M, Reddy A, Tidy JA, Evans D, Farrell PJ, Evans A, Gasco M, Gusterson B, Crook T. O'Nions J, et al. Among authors: crook t. Br J Cancer. 2001 Nov 16;85(10):1551-6. doi: 10.1054/bjoc.2001.2138. Br J Cancer. 2001. PMID: 11720444 Free PMC article.
ASPP proteins specifically stimulate the apoptotic function of p53.
Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L, Crook T, Lu X. Samuels-Lev Y, et al. Among authors: crook t. Mol Cell. 2001 Oct;8(4):781-94. doi: 10.1016/s1097-2765(01)00367-7. Mol Cell. 2001. PMID: 11684014
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